Hogeman P H, Veerman A J, de Waal F C, Bezemer P D, Huismans D R, van Zantwijk C H
Am J Pediatr Hematol Oncol. 1985 Fall;7(3):217-20. doi: 10.1097/00043426-198507030-00001.
In 96 cases of childhood acute lymphoblastic leukemia (ALL), handmirror cells (HMCs) were counted in cytospin preparations of washed lymphoblasts obtained at diagnosis. HMC counts were significantly lower in T-ALL as compared to C-ALL (p less than 0.001). In T-ALL and pre-T-ALL 2/35 cases had more than 10% HMCs; in C-ALL 22/41 cases had more than 10% HMCs. In two cases of B-ALL 19% and 36% HMCs were found. Thus, HMC expression in ALL is related to the immunological phenotype, especially found in ALLs originating along the B-cell lineage.
在96例儿童急性淋巴细胞白血病（ALL）中，对诊断时获取的洗涤后淋巴细胞的细胞涂片制备物中的手镜细胞（HMC）进行计数。与普通型ALL（C-ALL）相比，T细胞急性淋巴细胞白血病（T-ALL）中的HMC计数显著更低（p小于0.001）。在T-ALL和前T-ALL中，35例中有2例HMC超过10%；在C-ALL中，41例中有22例HMC超过10%。在2例B细胞急性淋巴细胞白血病（B-ALL）中，发现HMC分别为19%和36%。因此，ALL中的HMC表达与免疫表型相关，尤其在起源于B细胞系的ALL中发现。
