Tubiana N, Derre M, Carcassonne Y
Sem Hop. 1980;56(47-68):1993-7.
Immunological markers in acute lymphoid leukemia complete the cytological study and allow a new classification. 44 cases of acute lymphoïd leukemia were investigated for the presence of T and B membrane markers on bone marrow and/or peripheral blood lymphoblasts. 20 per cent of cases had T lymphoblasts: 10-90 per cent of the lymphoblastic cells exhibited T cells markers (E-Rosetting). 10 per cent of cases had B lymphoblasts: these cells have shown monoclonal surface immunoglobulin. 70 per cent of cases had "non T, non B" lymphoblasts: some of these lymphoblasts formed EAC-Rosettes. These techniques of lymphocytes studies are fruitful in furthering understanding of the structure function relationship of these cells.
急性淋巴细胞白血病中的免疫标记物完善了细胞学研究，并促成了一种新的分类方法。对44例急性淋巴细胞白血病患者的骨髓和/或外周血原始淋巴细胞进行了T和B膜标记物检测。20%的病例含有T原始淋巴细胞：10% - 90%的原始淋巴细胞表现出T细胞标记物（E花环形成）。10%的病例含有B原始淋巴细胞：这些细胞显示出单克隆表面免疫球蛋白。70%的病例含有“非T、非B”原始淋巴细胞：其中一些原始淋巴细胞形成了EAC花环。这些淋巴细胞研究技术有助于进一步理解这些细胞的结构与功能关系。
