Jiang Ke, Pan Cheng, Wang Limin, Wang Hao-Yang, Han Jianwei
Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center, Department of Fine Chemistry and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China.
National Center for Organic Mass Spectrometry in Shanghai, Shanghai Institute of Organic Chemistry, The Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
Beilstein J Org Chem. 2024 Apr 18;20:841-851. doi: 10.3762/bjoc.20.76. eCollection 2024.
Cyclic annulation involving diaryliodonium salts is an efficient tool for the construction of two or more chemical bonds in a one-pot process. -functionalized diaryliodonium salts have showcased distinct reactivity in the exploration of benzocyclization or arylocyclization. With this strategy of -ester-substituted diaryliodonium salts, herein, we utilized a copper catalyst to activate the C-I bond of diaryliodonium salts in the generation of aryl radicals, thus resulting in an annulation reaction with naphthols and substituted phenols. This approach yielded a diverse array of 3,4-benzocoumarin derivatives bearing various substituents.
涉及二芳基碘鎓盐的环化反应是一种在一锅法中构建两个或更多化学键的有效工具。-官能化二芳基碘鎓盐在苯并环化或芳基环化的探索中展现出独特的反应活性。利用这种-酯取代二芳基碘鎓盐的策略，在此我们使用铜催化剂在芳基自由基生成过程中活化二芳基碘鎓盐的C-I键，从而与萘酚和取代酚发生环化反应。该方法得到了一系列带有各种取代基的3,4-苯并香豆素衍生物。
