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神经内分泌肿瘤的诊断解剖影像学：发挥优势，克服劣势。

Diagnostic Anatomic Imaging for Neuroendocrine Neoplasms: Maximizing Strengths and Mitigating Weaknesses.

机构信息

From the Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

Department of Nuclear Medicine, The Chaim Sheba Medical Center, Tel Hashomer, Israel.

出版信息

J Comput Assist Tomogr. 2024;48(4):521-532. doi: 10.1097/RCT.0000000000001615. Epub 2024 Mar 23.

DOI:10.1097/RCT.0000000000001615
PMID:38657156
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11245376/
Abstract

Neuroendocrine neoplasms are a heterogeneous group of gastrointestinal and lung tumors. Their diverse clinical manifestations, variable locations, and heterogeneity present notable diagnostic challenges. This article delves into the imaging modalities vital for their detection and characterization. Computed tomography is essential for initial assessment and staging. At the same time, magnetic resonance imaging (MRI) is particularly adept for liver, pancreatic, osseous, and rectal imaging, offering superior soft tissue contrast. The article also highlights the limitations of these imaging techniques, such as MRI's inability to effectively evaluate the cortical bone and the questioned cost-effectiveness of computed tomography and MRI for detecting specific gastric lesions. By emphasizing the strengths and weaknesses of these imaging techniques, the review offers insights into optimizing their utilization for improved diagnosis, staging, and therapeutic management of neuroendocrine neoplasms.

摘要

神经内分泌肿瘤是一组异质性的胃肠道和肺部肿瘤。它们多样的临床表现、多变的位置和异质性给诊断带来了显著的挑战。本文深入探讨了对其检测和特征描述至关重要的成像方式。计算机断层扫描（CT）是初始评估和分期的基础。与此同时，磁共振成像（MRI）特别擅长于肝脏、胰腺、骨骼和直肠成像，提供了更好的软组织对比度。文章还强调了这些成像技术的局限性，例如 MRI 无法有效评估皮质骨，以及 CT 和 MRI 用于检测特定胃部病变的成本效益受到质疑。通过强调这些成像技术的优缺点，这篇综述提供了优化其应用的见解，以改善神经内分泌肿瘤的诊断、分期和治疗管理。

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Accurate non-invasive grading of nonfunctional pancreatic neuroendocrine tumors with a CT derived radiomics signature.
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Comparison of Metastatic Patterns Among Neuroendocrine Tumors, Neuroendocrine Carcinomas, and Nonneuroendocrine Carcinomas of Various Primary Organs.比较不同原发器官的神经内分泌肿瘤、神经内分泌癌和非神经内分泌癌的转移模式。
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