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B 型超声扫描、超广角眼底成像和间接检眼镜在检测白内障眼中视网膜裂孔的比较。

Comparison of B-Scan ultrasonography, ultra-widefield fundus imaging, and indirect ophthalmoscopy in detecting retinal breaks in cataractous eyes.

机构信息

Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.

NHC Key Laboratory of Myopia (Fudan University); Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.

出版信息

Eye (Lond). 2024 Sep;38(13):2619-2624. doi: 10.1038/s41433-024-03093-2. Epub 2024 Apr 24.

Abstract

BACKGROUND/OBJECTIVES: To evaluate the diagnostic performance of B-scan kinetic ultrasonography (USG), standard ultra-widefield (UWF) imaging, and indirect ophthalmoscopy (IDO) in retinal break detection in cataractous eyes.

SUBJECTS/METHODS: We consecutively enrolled 126 cataract patients (including 246 eyes) with no comorbidities that could decrease best corrected visual acuity (BCVA). Three index tests (USG, nonmydriatic UWF, and mydriatic IDO) were performed preoperatively to screen for retinal breaks. One week after cataract extraction, a dilated IDO examination was repeated for the definitive diagnosis of retinal break as the reference standard. The sensitivity, specificity, Youden index (YI), and predictive values of each index test were calculated according to postoperative ophthalmoscopic findings. A deep-learning nomogram was developed to quantify the risk of retinal break presence using patients' baseline data and findings reported from preoperative ophthalmic tests.

RESULTS

Fifty-two eyes (21%) were excluded from appropriate preoperative UWF imaging because of massive lens opacity. The BCVA cutoff point with maximum YI indicating UWF applicability was 0.6 logMAR (YI = 0.3; area under curve [AUC] = 0.7). Among all 246 eyes, preoperative IDO, USG, and UWF showed fair interobserver agreement (all κ > 0.2). According to postoperative IDO findings, the index tests with the highest sensitivity and specificity were USG (100%) and preoperative IDO (99%), respectively.

CONCLUSIONS

For cataractous eyes without vision-impairing comorbidities, a BCVA better than 0.6 logMAR (Snellen acuity, 20/80) allows for appropriate nonmydriatic standard UWF imaging. In a high-volume clinic equipped with skilled ophthalmic examiners, screening with USG followed by directed IDO allows the efficient identification of retinal breaks in cataractous eyes.

摘要

背景/目的:评估 B 型扫描动态超声(USG)、标准超广角(UWF)成像和间接检眼镜(IDO)在白内障眼中视网膜裂孔检测中的诊断性能。

受试者/方法:我们连续招募了 126 名无任何可能降低最佳矫正视力(BCVA)的合并症的白内障患者(包括 246 只眼)。三种索引测试(USG、非散瞳超广角和散瞳 IDO)在术前进行,以筛查视网膜裂孔。白内障摘除术后一周,重复散瞳 IDO 检查,作为参考标准,明确诊断视网膜裂孔。根据术后眼科检查结果,计算每种索引测试的灵敏度、特异性、约登指数(YI)和预测值。使用患者的基线数据和术前眼科检查报告的结果,开发了一种深度学习列线图,以量化视网膜裂孔存在的风险。

结果

由于晶状体混浊严重,52 只眼(21%)被排除在适当的术前 UWF 成像之外。具有最大 YI 指示 UWF 适用性的 BCVA 截断点为 0.6 logMAR(YI=0.3;曲线下面积[AUC]=0.7)。在所有 246 只眼中,术前 IDO、USG 和 UWF 显示出良好的观察者间一致性(所有κ值>0.2)。根据术后 IDO 检查结果,具有最高灵敏度和特异性的指标测试分别为 USG(100%)和术前 IDO(99%)。

结论

对于没有视力受损合并症的白内障眼,如果 BCVA 优于 0.6 logMAR(Snellen 视力,20/80),则允许进行适当的非散瞳标准 UWF 成像。在配备熟练眼科检查人员的大容量诊所中,USG 筛查后进行有针对性的 IDO 检查,可以有效地识别白内障眼中的视网膜裂孔。

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