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Curr Opin Ophthalmol. 2021 May 1;32(3):198-202. doi: 10.1097/ICU.0000000000000752.
Symptomatic vitreous opacities are increasingly recognized as a significant burden to patient well-being. There is growing interest in the use of vitrectomy or laser treatment to address these problems. This review is intended to update current assessment, management, and risks of treatment for persistent severely symptomatic vitreous opacities.
Despite studies showing the value of quantitative ultrasound, reading speed measurements, and contrast sensitivity for assessing dysfunction caused by vitreous opacities, the decision of whether to proceed with surgery remains a very subjective, clinical one. Visual Function Questionnaire-25 score studies show a very large improvement postvitrectomy consistent with relief from symptoms and patient satisfaction. The risk of retinal tear and detachment appears to be higher than in most conditions treated with vitrectomy.
Vitrectomy for the management of severe vitreous opacities is increasingly accepted because of the tremendous relief of symptoms reported by patients. The risks of retinal tear and detachment remain a concern, particularly in patients who have an attached posterior hyaloid. Yttrium-aluminum-garnet laser treatment of floaters may offer benefit in a subset of patients but appears to be less definitive than vitrectomy, and also may carry significant risk.
有症状的玻璃体混浊日益被认为是患者健康的重大负担。越来越多的人对玻璃体切割术或激光治疗这些问题感兴趣。本文旨在更新目前对持续性严重有症状的玻璃体混浊的评估、处理和治疗风险。
尽管研究表明定量超声、阅读速度测量和对比敏感度在评估玻璃体混浊引起的功能障碍方面具有价值,但是否进行手术的决定仍然是一个非常主观的临床决策。视觉功能问卷-25 评分研究表明,玻璃体切割术后有很大的改善,与症状缓解和患者满意度一致。视网膜裂孔和脱离的风险似乎高于大多数玻璃体切割术治疗的情况。
由于患者报告的症状缓解程度很大,玻璃体切割术越来越多地被用于治疗严重的玻璃体混浊。视网膜裂孔和脱离的风险仍然是一个关注点,特别是在有后玻璃体粘连的患者中。钇铝石榴石激光治疗飞蚊症可能对一部分患者有益,但似乎不如玻璃体切割术确定,而且也可能有很大的风险。