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本文引用的文献

1
Clinical Profile and Treatment Outcome in Scrub Typhus Patients in Central India.印度中部丛林斑疹伤寒患者的临床特征和治疗结果。
J Assoc Physicians India. 2021 Sep;69(9):11-12.
2
The burden of scrub typhus in India: A systematic review.印度恙虫病负担:系统评价。
PLoS Negl Trop Dis. 2021 Jul 27;15(7):e0009619. doi: 10.1371/journal.pntd.0009619. eCollection 2021 Jul.
3
Scrub typhus-related hepatotoxicity: The Indian scenario.恙虫病相关性肝毒性:印度情况。
Trop Doct. 2021 Apr;51(2):228-231. doi: 10.1177/0049475521991353. Epub 2021 Feb 21.
4
Scrub typhus strikes back: Are we ready?恙虫病卷土重来:我们准备好了吗?
Med J Armed Forces India. 2019 Jan;75(1):8-17. doi: 10.1016/j.mjafi.2018.12.018. Epub 2019 Jan 10.
5
Scrub typhus in pregnancy: Maternal and fetal outcomes.妊娠期恙虫病:母婴结局
Obstet Med. 2016 Dec;9(4):164-166. doi: 10.1177/1753495X16638952. Epub 2016 May 5.
6
A Systematic Review of Mortality from Untreated Scrub Typhus (Orientia tsutsugamushi).未经治疗的恙虫病(恙虫东方体)死亡率的系统评价
PLoS Negl Trop Dis. 2015 Aug 14;9(8):e0003971. doi: 10.1371/journal.pntd.0003971. eCollection 2015.
7
Genome-wide association studies in biliary atresia.胆道闭锁的全基因组关联研究。
Wiley Interdiscip Rev Syst Biol Med. 2015 Sep-Oct;7(5):267-73. doi: 10.1002/wsbm.1303. Epub 2015 May 11.
8
A case series of scrub typhus in obstetrics.产科恙虫病病例系列
J Clin Diagn Res. 2014 Dec;8(12):OR01-3. doi: 10.7860/JCDR/2014/9718.5258. Epub 2014 Dec 5.
9
Pregnancy outcome in relation to treatment of murine typhus and scrub typhus infection: a fever cohort and a case series analysis.与鼠型斑疹伤寒和恙虫病感染治疗相关的妊娠结局:发热队列研究和病例系列分析
PLoS Negl Trop Dis. 2014 Nov 20;8(11):e3327. doi: 10.1371/journal.pntd.0003327. eCollection 2014 Nov.
10
Update on the diagnosis and classification of fetal growth restriction and proposal of a stage-based management protocol.胎儿生长受限的诊断与分类更新及基于阶段的管理方案建议
Fetal Diagn Ther. 2014;36(2):86-98. doi: 10.1159/000357592. Epub 2014 Jan 23.

妊娠期恙虫病:两例报告。

Scrub typhus in pregnancy: A report of two cases.

作者信息

Selvan Advika Thamarai, Agarwal Ishita, Behera Bijayini, Singh Sweta

机构信息

Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Bhubaneswar, India.

Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, India.

出版信息

Obstet Med. 2024 Mar;17(1):58-60. doi: 10.1177/1753495X221122593. Epub 2022 Sep 18.

DOI:10.1177/1753495X221122593
PMID:38660322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11037195/
Abstract

Scrub typhus shows a high prevalence in South-East Asia. In pregnant females, it can cause both maternal and fetal adverse outcomes. We report a case series of two women with scrub typhus and their varied outcomes. A 25-year-old primigravida treated for scrub typhus at 23 weeks' gestation presented at 34 weeks with stage three fetal growth restriction (FGR). Caesarean delivery was performed. The neonate had biliary atresia. A 24-year-old primigravida at 31 weeks' gestation was referred from a local hospital due to scrub typhus induced multi-organ dysfunction. She had FGR stage 1 with oligohydramnios. Emergency caesarean delivery was performed in view of acute fetal bradycardia. There is an emerging need for research to reassess what is already known about scrub typhus in pregnancy and to develop techniques for its treatment inorder to achieve a positive maternal and neonatal outcome in these cases.

摘要

恙虫病在东南亚地区高发。对于孕妇而言,它可导致母婴不良结局。我们报告了两例恙虫病女性患者及其不同结局的病例系列。一名25岁初产妇在妊娠23周时接受恙虫病治疗,34周时出现三级胎儿生长受限(FGR)。实施了剖宫产。新生儿患有胆道闭锁。一名24岁初产妇在妊娠31周时因恙虫病诱发多器官功能障碍从当地医院转诊而来。她患有一级FGR伴羊水过少。鉴于急性胎儿心动过缓,实施了急诊剖宫产。迫切需要开展研究,重新评估关于妊娠期恙虫病的已知情况,并开发其治疗技术,以便在这些病例中实现母婴良好结局。