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胸部放射治疗后肺动脉假性动脉瘤:一例报告并文献复习

Pulmonary artery pseudoaneurysm after thoracic radiation therapy: A case report and review of the literature.

作者信息

Maessen Gerdinique G C, Hoffman Thijs T W, Graat-Verboom Lidwien L, van Leersum Marc M, Mager Hans-Jurgen J J

机构信息

Pulmonology St. Antonius Ziekenhuis Nieuwegein The Netherlands.

Pulmonology Maxima Medisch Centrum Eindhoven The Netherlands.

出版信息

Respirol Case Rep. 2024 Apr 24;12(4):e01349. doi: 10.1002/rcr2.1349. eCollection 2024 Apr.

DOI:10.1002/rcr2.1349
PMID:38660341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11040564/
Abstract

Pulmonary artery pseudoaneurysm (PAP) is a rare cause of hemoptysis. Potential causes include trauma, infection, or medical interventions. There is a risk of rupture, which is associated with a high mortality rate. We describe a 72-year-old patient, with a past medical history of a lung carcinoma for which she was treated with chemoradiotherapy 6 years prior, who presented with hemoptysis. She was hemodynamically stable and there were no other complaints. CT angiography of the thorax showed a PAP originating from a branch of the right pulmonary artery in the previously irradiated area. The patient was successfully treated by an embolization with plugs. Treatment of lung carcinoma with chemoradiotherapy can result in the development of a PAP. Clinicians should be aware of this complication, even years after the therapy. In literature, only a few cases of PAP in patients treated with (chemo)radiotherapy for lung cancer are described, with a maximum interval up to 7 years.

摘要

肺动脉假性动脉瘤(PAP)是咯血的罕见原因。潜在病因包括创伤、感染或医疗干预。存在破裂风险,这与高死亡率相关。我们描述了一名72岁女性患者,她6年前曾因肺癌接受放化疗,此次因咯血就诊。她血流动力学稳定,无其他不适主诉。胸部CT血管造影显示在先前放疗区域有一个源自右肺动脉分支的PAP。该患者通过栓塞术成功治疗。肺癌放化疗可导致PAP形成。临床医生应意识到这种并发症,即使在治疗多年后也需警惕。文献中仅描述了少数肺癌放化疗患者发生PAP的病例,最长间隔时间为7年。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7706/11040564/6b9ee104fe16/RCR2-12-e01349-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7706/11040564/2221cade1b90/RCR2-12-e01349-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7706/11040564/d8547bfba87e/RCR2-12-e01349-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7706/11040564/6b9ee104fe16/RCR2-12-e01349-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7706/11040564/2221cade1b90/RCR2-12-e01349-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7706/11040564/d8547bfba87e/RCR2-12-e01349-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7706/11040564/6b9ee104fe16/RCR2-12-e01349-g003.jpg

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J Clin Med. 2023 May 31;12(11):3796. doi: 10.3390/jcm12113796.
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Embolic Pneumonectomy for the Treatment of Proximal Pulmonary Artery Pseudoaneurysm.栓塞性肺切除术治疗近端肺动脉假性动脉瘤
Cureus. 2022 Jul 1;14(7):e26487. doi: 10.7759/cureus.26487. eCollection 2022 Jul.
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Late presentation of pulmonary artery pseudoaneurysm following bronchovascular sleeve resection of lung.肺动脉假性动脉瘤在肺血管袖状切除术治疗后出现迟发。
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