Gunderson J G, Siever L J
Schizophr Bull. 1985;11(4):532-7. doi: 10.1093/schbul/11.4.532.
The schizotypal personality category introduced in DSM-III reflects an initial effort to organize psychiatric diagnosis on a biogenetic basis. The schizotypal diagnosis is intended to reflect a genetic association with schizophrenia. One result of this inclusion has been to stimulate a growing body of evidence about its validity--evidence that is reviewed in this issue by Kendler, Torgersen, Siever, and Stone. These studies suggest that criteria which emphasize interpersonal and social trait disabilities are more specific to a schizotype than criteria which stress psychotic-like symptoms. As a result, we suggest that future research on this patient group should broaden its criteria base. However, even if revisions increase the biogenetic specificity of this category, we believe its treatment will remain unclear, and models for its pathogenesis and relationship to schizophrenia will need to remain complex.
《精神疾病诊断与统计手册》第三版引入的分裂型人格类别反映了在生物遗传学基础上组织精神疾病诊断的初步尝试。分裂型人格诊断旨在反映与精神分裂症的遗传关联。将其纳入的一个结果是激发了越来越多关于其有效性的证据——肯德勒、托格森、西弗和斯通在本期对此类证据进行了综述。这些研究表明,强调人际和社会特质缺陷的标准比强调类精神病症状的标准更具分裂型人格的特异性。因此,我们建议未来针对该患者群体的研究应拓宽其标准基础。然而,即使修订增加了该类别的生物遗传学特异性,我们认为其治疗仍将不明朗,其发病机制以及与精神分裂症关系的模型仍需保持复杂性。