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住院医师实施的同日双侧360度选择性激光小梁成形术治疗开角型青光眼的有效性和安全性

Effectiveness and Safety of Resident-Performed Same-Day Bilateral 360-Degree Selective Laser Trabeculoplasty in Patients With Open Angle Glaucoma.

作者信息

Xiao Jason, Si Zhuangjun, Qiu Mary

机构信息

Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL.

Cole Eye Institute, Cleveland Clinic, Cleveland, OH.

出版信息

J Glaucoma. 2025 May 1;34(5):388-393. doi: 10.1097/IJG.0000000000002526. Epub 2024 Dec 16.

Abstract

PRCIS

Resident-performed same-day bilateral selective laser trabeculoplasty are safe and effective for patients with primary open angle glaucoma or ocular hypertension.

PURPOSE

To assess the efficacy and safety of resident-performed same-day bilateral 360-degree selective laser trabeculoplasty (SLT).

PATIENTS AND METHODS

A retrospective chart review was performed for patients who received bilateral, resident-performed SLT at the University of Chicago from January 1, 2020 to December 31, 2022 under the supervision of 1 glaucoma surgeon (M.Q.). Patients were included in this analysis if they underwent same-day bilateral 360-degree SLT and had at least 6 months of follow-up available. Data were collected on visual acuity, intraocular pressure (IOP), number of IOP-lowering medications, and complications for up to 2 years after the procedure.

RESULTS

There were 48 patients included in this analysis, and the diagnosis was either primary open angle glaucoma (85.4%) or ocular hypertension (14.6%). For patients whose SLT goal was to lower IOP (n=38), the mean baseline IOP in right eyes (OD) was 19.2 mm Hg on 2.1 medications, and in left eyes (OS) was 19.5 mm Hg on 2.1 medications. At the final follow-up (mean 519 d), the mean IOP in the right eyes was 15.8 mm Hg on 2.0 medications, and in the left eyes was 15.8 mm Hg OS on 2.2 medications, resulting in an IOP reduction of 17.6% OD and of 18.8% OS. For patients whose SLT goal was to lower medication number (n=10), the mean baseline IOP in right eyes was 16.7 mm Hg on 2.3 medications, and in left eyes was 16.4 mm Hg OS on 2.3 medications. At the final follow-up (mean 528 d), the mean IOP in the right eye was 17.6 mm Hg on 1.1 medications, and in the left eye was 16.3 mm Hg OS on 1.1 medications, resulting in a medication reduction of 1.1 fewer medications OD and 1.1 fewer medications OS. One patient experienced a 6 mm Hg IOP rise above baseline 4 weeks after SLT, and another developed 2 small, focal areas of peripheral anterior synechiae. Six (12.5%) patients underwent additional IOP-lowering surgery during the chart review period.

CONCLUSIONS

Resident-performed same-day bilateral 360-degree SLT was effective and associated with minimal complications, with rates comparable to those of attending-performed SLT in the literature. SLT can be individualized to patients' goals of IOP-lowering or medication reduction. Teaching institutions can consider incorporating this method of education for appropriate patients with primary open angle glaucoma or ocular hypertension.

摘要

PRCIS

住院医生实施的同日双侧选择性激光小梁成形术对原发性开角型青光眼或高眼压症患者是安全有效的。

目的

评估住院医生实施的同日双侧360度选择性激光小梁成形术(SLT)的疗效和安全性。

患者与方法

对2020年1月1日至2022年12月31日在芝加哥大学1名青光眼外科医生(M.Q.)监督下接受双侧住院医生实施的SLT的患者进行回顾性病历审查。如果患者接受了同日双侧360度SLT且有至少6个月的可用随访,则纳入本分析。收集术后长达2年的视力、眼压(IOP)、降低眼压药物数量和并发症的数据。

结果

本分析纳入48例患者,诊断为原发性开角型青光眼(85.4%)或高眼压症(14.6%)。对于SLT目标是降低眼压的患者(n = 38),右眼(OD)的平均基线眼压为19.2 mmHg,使用2.1种药物,左眼(OS)为19.5 mmHg,使用2.1种药物。在最终随访时(平均519天),右眼的平均眼压为15.8 mmHg,使用2.0种药物,左眼为15.8 mmHg OS,使用2.2种药物,右眼眼压降低17.6%,左眼降低18.8%。对于SLT目标是减少药物数量的患者(n = 10),右眼的平均基线眼压为16.7 mmHg,使用2.3种药物,左眼为16.4 mmHg OS,使用2.3种药物。在最终随访时(平均528天),右眼的平均眼压为17.6 mmHg,使用1.1种药物,左眼为16.3 mmHg OS,使用1.1种药物,右眼药物减少1.1种,左眼减少1.1种。1例患者在SLT后4周眼压比基线升高6 mmHg,另1例出现2个小的局限性周边前粘连区域。在病历审查期间,6例(12.5%)患者接受了额外的降眼压手术。

结论

住院医生实施的同日双侧360度SLT是有效的,并发症极少,发生率与文献中主治医生实施的SLT相当。SLT可以根据患者降低眼压或减少药物的目标进行个体化。教学机构可以考虑将这种教育方法纳入适合的原发性开角型青光眼或高眼压症患者。

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