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医学加速器中的突破性电子中子多响应微型剂量测定/能谱测定

Breakthrough electroneutron multi-response miniature dosimetry/spectrometry in medical accelerator.

作者信息

Sohrabi Mehdi, Malekitakbolagh Maryam, Nedaei Hasan Ali

机构信息

Health Physics and Dosimetry Research Laboratory, Department of Energy Engineering and Physics, Amirkabir University of Technology, Tehran, Iran.

Department of Radiotherapy Oncology, Cancer Institute, University of Medical Sciences, Tehran, Iran.

出版信息

Sci Rep. 2024 Apr 25;14(1):9557. doi: 10.1038/s41598-024-59871-1.

Abstract

Breakthrough multi-response miniature dosimetry/spectrometry of electroneutrons (EN) was made on surface and in-depths of whole-body polyethylene phantom under 10 cm × 10 cm electron beam of 20 MV Varian Clinac 2100C electron medical accelerator commonly applied for prostate treatment. While dosimetry/spectrometry of photoneutrons (PN) has been well characterized for decades, those of ENs lagged behind due to very low EN reaction cross section and lack of sensitive neutron dosimeters/spectrometers meeting neutron dosimetry requirements. Recently, Sohrabi "miniature neutron dosimeter/spectrometer" and "Stripe polycarbonate dosimeter" have broken this barrier and determined seven EN ambient dose equivalent (ENDE) (µSv.Gy) responses from electron beam and from albedo ENs including beam thermal (21 ± 2.63), albedo thermal (43 ± 3.70), total thermal (64 ± 6.33), total epithermal (32 ± 3.90), total fast (112.00), total thermal + epithermal (l96 ± 10), and total thermal + epithermal + fast (208 ± 10.23) ENs. Having seven ENDE responses of this study and seven PNDE responses of previous study with the same accelerator obtained at identical conditions by the same principle author provided the opportunity to compare the two sets of responses. The PNDE (µSv.Gy) responses have comparatively higher values and 22.60 times at isocenter which provide for the first time breakthrough ENDE responses not yet reported in any studies before worldwide.

摘要

在常用于前列腺治疗的20 MV瓦里安Clinac 2100C电子医用加速器产生的10 cm×10 cm电子束下,对全身聚乙烯模型的表面和深度进行了突破性的电子中子(EN)多响应微型剂量测定/能谱测定。虽然光中子(PN)的剂量测定/能谱测定已得到几十年的充分表征,但由于EN反应截面非常低,且缺乏满足中子剂量测定要求的灵敏中子剂量计/能谱仪,EN的剂量测定/能谱测定一直滞后。最近,索拉比的“微型中子剂量计/能谱仪”和“条纹聚碳酸酯剂量计”打破了这一障碍,确定了来自电子束和反照率EN的七种EN环境剂量当量(ENDE)(µSv·Gy)响应,包括束热(21±2.63)、反照率热(43±3.70)、总热(64±6.33)、总超热(32±3.90)、总快中子(112.00)、总热+超热(196±10)和总热+超热+快中子(208±10.23)EN。本研究的七种ENDE响应和同一作者在相同条件下使用同一加速器通过相同原理获得的先前研究的七种PNDE响应,提供了比较这两组响应的机会。PNDE(µSv·Gy)响应在等中心处的值相对较高,是ENDE响应的22.60倍,这首次提供了全球此前任何研究中均未报道过的突破性ENDE响应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c21c/11045717/17f6a81a1c98/41598_2024_59871_Fig1_HTML.jpg

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