2005年至2014年期间，加利福尼亚州基于卫星估算的有机碳、元素碳、硝酸盐和硫酸盐等细颗粒物（PM2.5）物种浓度与出生体重和早产之间的关联。

Associations between satellite-derived estimates of PM2.5 species concentrations for organic carbon, elemental carbon, nitrate, and sulfate with birth weight and preterm birth in California during 2005-2014.

作者信息

Reuther Patrick S, Geng Guannan, Liu Yang, Darrow Lyndsey A, Strickland Matthew J

机构信息

School of Public Health, University of Nevada, Reno, Reno, NV, USA.

Tsinghua University, Beijing, China.

出版信息

J Expo Sci Environ Epidemiol. 2025 Apr;35(2):233-241. doi: 10.1038/s41370-024-00673-y. Epub 2024 Apr 25.

DOI:10.1038/s41370-024-00673-y

PMID:38664552

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11502512/

Abstract

BACKGROUND

Characterizing the spatial distribution of PM species concentrations is challenging due to the geographic sparsity of the stationary monitoring network. Recent advances have enabled valid estimation of PM species concentrations using satellite remote sensing data for use in epidemiologic studies.

OBJECTIVE

In this study, we used satellite-based estimates of ambient PM species concentrations to estimate associations with birth weight and preterm birth in California.

METHODS

Daily 24 h averaged ground-level PM species concentrations of organic carbon, elemental carbon, nitrate, and sulfate were estimated during 2005-2014 in California at 1 km resolution. Birth records were linked to ambient pollutant exposures based on maternal residential zip code. Linear regression and Cox regression were conducted to estimate the effect of 1 µg/m increases in PM species concentrations on birth weight and preterm birth.

RESULTS

Analyses included 4.7 million live singleton births having a median 28 days with exposure measurements per pregnancy. In single pollutant models, the observed changes in mean birth weight (per 1 µg/m increase in speciated PM concentrations) were: organic carbon -3.12 g (CI: -4.71, -1.52), elemental carbon -14.20 g (CI: -18.76, -9.63), nitrate -5.51 g (CI: -6.79, -4.23), and sulfate 9.26 g (CI: 7.03, 11.49). Results from multipollutant models were less precise due to high correlation between pollutants. Associations with preterm birth were null, save for a negative association between sulfate and preterm birth (Hazard Ratio per 1 µg/m increase: 0.973 CI: 0.958, 0.987).

摘要

背景

由于固定监测网络的地理稀疏性，确定颗粒物（PM）物种浓度的空间分布具有挑战性。最近的进展使得利用卫星遥感数据有效估计PM物种浓度用于流行病学研究成为可能。

目的

在本研究中，我们使用基于卫星的环境PM物种浓度估计值来估计加利福尼亚州出生体重和早产之间的关联。

方法

2005 - 2014年期间，以1公里分辨率估计了加利福尼亚州每日24小时平均地面有机碳、元素碳、硝酸盐和硫酸盐等PM物种浓度。根据产妇居住邮政编码将出生记录与环境污染物暴露情况相关联。进行线性回归和Cox回归以估计PM物种浓度每增加1μg/m³对出生体重和早产的影响。

结果

分析纳入了470万例单胎活产，每次妊娠暴露测量的中位数为28天。在单污染物模型中，观察到的平均出生体重变化（特定PM浓度每增加1μg/m³）为：有机碳 -3.12克（置信区间：-4.71，-1.52），元素碳 -14.20克（置信区间：-18.76，-9.63），硝酸盐 -5.51克（置信区间：-6.79，-4.23），硫酸盐9.26克（置信区间：7.03，11.49）。由于污染物之间的高度相关性，多污染物模型的结果不太精确。除了硫酸盐与早产之间的负相关（每增加1μg/m³的风险比：0.973，置信区间：0.958，0.987）外，与早产的关联均为零。