Department of Anaesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan, Dongcheng District, Beijing, China.
Medical Research Centre, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Respir Res. 2024 Apr 25;25(1):184. doi: 10.1186/s12931-024-02799-x.
In conventional practice, the left double lumen tube (DLT) is rotated 90° counterclockwise when the endobronchial cuff passes glottis. Success rate upon the first attempt is < 80%, likely owing to varying morphology of the bronchial bifurcation.
We conducted a randomized controlled trial to compare 90° counterclockwise rotation versus individualized degree of rotation in adult patients undergoing elective thoracic surgery using left DLT. The degree of rotation in the individualized group was based on the angle of the left main bronchi as measured on computed tomography (CT). The primary outcome was the first attempt left DLT placement success rate.
A total of 556 patients were enrolled: 276 in the control group and 280 in the individualized group. The average angle of the left main bronchi was 100.6±9.5° (range 72° to 119°). The first attempt left DLT placement success rate was 82.6% (228/276) in the control group versus 91.4% (256/280) in the individualized group (P=0.02, χ2 test). The rate of carina mucosal injury, as measured at 30 min after the start of surgery under fibreoptic bronchoscopy, was significantly lower in individualized group than control group (14.0% versus 19.6%, P=0.041). The individualized group also had lower rate of postoperative sore throat (29.4% versus 44.0%, P<0.001) and hoarseness (16.8% versus 24.7%, P<0.05).
Individualized rotation of left DLT based on the angle of the left main bronchi on preoperative CT increased first attempt success rate in adult patients undergoing elective thoracic surgery.
The trial is registered at Chinese Clinical Trial Registry (ChiCTR2100053349; principal investigator Xiang Quan, date of registration November 19, 2021).
在常规实践中,当支气管内套囊通过声门时,将左侧双腔管(DLT)逆时针旋转 90°。首次尝试的成功率<80%,可能是由于支气管分叉的形态各异。
我们进行了一项随机对照试验,比较了在接受择期胸外科手术的成年患者中,使用左侧 DLT 时,逆时针旋转 90°与个体化旋转角度的效果。个体化组的旋转角度基于 CT 测量的左主支气管角度。主要结局是左侧 DLT 首次尝试放置成功率。
共纳入 556 例患者:对照组 276 例,个体化组 280 例。左主支气管的平均角度为 100.6±9.5°(范围 72°至 119°)。对照组首次尝试左侧 DLT 放置成功率为 82.6%(228/276),个体化组为 91.4%(256/280)(P=0.02,卡方检验)。纤维支气管镜检查术开始后 30 分钟测量的隆嵴黏膜损伤发生率,个体化组显著低于对照组(14.0%比 19.6%,P=0.041)。个体化组术后咽痛发生率(29.4%比 44.0%,P<0.001)和声音嘶哑发生率(16.8%比 24.7%,P<0.05)也较低。
基于术前 CT 测量的左主支气管角度对左侧 DLT 进行个体化旋转可提高择期胸外科手术成年患者的首次尝试成功率。
该试验在中国临床试验注册中心注册(ChiCTR2100053349;主要研究者项全,注册日期 2021 年 11 月 19 日)。