Yu Wei, Wang Zijian, Gao Dapeng, Zhang Wei, Jin Wen, Ma Xuesong, Qi Sihua
Department of Anaesthesiology, Fourth Affiliated Hospital of Harbin Medical University, 37 Yiyuan Road, Harbin, 150001, Heilongjiang Province, China.
BMC Anesthesiol. 2018 Sep 18;18(1):130. doi: 10.1186/s12871-018-0596-3.
A right-sided double-lumen tube (R-DLT) tends to obstruct the right upper lobe intraoperatively due to anatomical distortion during surgery. If the R-DLT is poorly matched with the patient's airway anatomy, it will not be possible to correctly replace the tube with a fiberoptic bronchoscope (FOB). In our study, we aimed to explore an efficient method for difficult repositioning caused by right upper lobe occlusion during surgery: repositioning the R-DLT from the right main bronchus into the left main bronchus. The current study was designed to assess the efficacy and safety of this method.
Sixty adult patients scheduled to undergo left-sided thoracic surgery were randomly assigned to two groups. With the patient in the right lateral position during surgery, the R-DLT was pulled back to the trachea while being rotated 90° clockwise; it was then either rotated 90° clockwise for placement into the left main bronchus (Group L) or rotated 90° anticlockwise and returned to the right main bronchus (Group R) using FOB guidance. The primary outcomes included clinical performance, which was measured by intubation time, and the quality of lung collapse. A secondary outcome was safety, which was determined according to bronchial injury and vocal cord injury.
The median intubation time (IQR [range]) required for placement of a R-DLT into the left main bronchus was shorter than the time required for placement into the right main bronchus (15.0 s [IQR, 12.0 to 20.0 s]) vs 23.5 s [IQR, 14.5 to 65.8 s], P = 0.005). The groups showed comparable overall results for the quality of lung collapse during the total period of one-lung ventilation (P = 1.000). The numbers of patients with bronchial injuries or vocal cord injuries were also comparable between groups (Group R, 11/30 vs. Group L 8/30, P = 0.580 for bronchus injuries; Group R, 15/30 vs. Group L 13/30, P = 0.796 for vocal cord injuries).
Repositioning a R-DLT from the right main bronchus into the left main bronchus had good clinical performance without causing additional injury. This may be an efficient method for the difficult repositioning of a R-DLT due to right upper lobe occlusion during surgery.
Chinese Clinical Trial Registry, ChiCTR-IPR-15006933 , registered on 15 August 2015.
右侧双腔支气管导管(R-DLT)在手术过程中往往会因解剖结构改变而导致右肺上叶术中阻塞。如果R-DLT与患者气道解剖结构匹配不佳,就无法通过纤维支气管镜(FOB)正确更换导管。在我们的研究中,我们旨在探索一种针对手术中右肺上叶阻塞导致的困难重新定位的有效方法:将R-DLT从右主支气管重新定位到左主支气管。本研究旨在评估该方法的有效性和安全性。
60例计划行左侧胸科手术的成年患者随机分为两组。手术中患者取右侧卧位时,将R-DLT拉回气管并顺时针旋转90°;然后使用FOB引导,要么顺时针旋转90°放入左主支气管(L组),要么逆时针旋转90°回到右主支气管(R组)。主要结局包括临床操作表现,通过插管时间衡量,以及肺萎陷质量。次要结局是安全性,根据支气管损伤和声门损伤确定。
将R-DLT放入左主支气管所需的中位插管时间(IQR[范围])短于放入右主支气管所需时间(15.0秒[IQR,12.0至20.0秒])对比23.5秒[IQR,14.5至65.8秒],P = 0.005)。在单肺通气的整个期间,两组在肺萎陷质量方面的总体结果相当(P = 1.000)。两组间支气管损伤或声门损伤患者数量也相当(R组,11/30对比L组8/30,支气管损伤P = 0.580;R组,15/30对比L组13/30,声门损伤P = 0.796)。
将R-DLT从右主支气管重新定位到左主支气管具有良好的临床操作表现,且不会造成额外损伤。这可能是一种针对手术中因右肺上叶阻塞导致的R-DLT困难重新定位的有效方法。
中国临床试验注册中心,ChiCTR-IPR-15006933,于2015年8月15日注册。