Department of Scientific Research, Faculty of General Family Medicine, the First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China.
Department of Health Statistics, Faculty of Public Health, Shaanxi University of Chinese Medicine, Xi'an, Shannxi, China.
Front Public Health. 2024 Apr 11;12:1276536. doi: 10.3389/fpubh.2024.1276536. eCollection 2024.
The aims of this survey were to investigate the public awareness of drug clinical trials (DCTs) and willingness to participate the DCTs, and provide references for propaganda and science popularization of DCTs.
A self-designed questionnaire named "an online survey questionnaire on public awareness of DCTs" was used to conduct an online survey from January to March 2022. The demographic characteristics and the response of participants to the awareness and willingness to participate the DCTs were collected. The factors affecting the public awareness of DCTs were analyzed by single factor and binary logistic regression analysis.
One thousand three hundred eighty valid questionnaires were collected, and the respondents' awareness rate of DCTs was 61.1%. Thirteen demographic characteristics including age, gender, education, occupation, work fields, household type, marital status, city type, income, medical insurance, medical expenditure, pressure to seek medical care, financial pressure, both significantly affected the qualified rate of participants' awareness of DCTs ( < 0.001) by single factor analysis. Binary logistic regression analysis indicated that education level, work fields, city type, medical insurance, and medical expenditure affected independently the participants' awareness rate of DCTs ( < 0.001). 52.9% of the participants were willing to take part in DCTs. "to promote medical progress" (54.4%) or "believe doctors" (31.1%) were the most frequent reasons for subjects participating in DCTs.
The public awareness rate of DCTs and the willingness to participate in drug clinical were significantly affected by the demographic characteristics of subjects. Thus, targeting the needs of the public, propaganda, and science popularization of DCTs should be carried out and served public health.
本调查旨在了解公众对药物临床试验(DCT)的认知度和参与意愿,为 DCT 的宣传和科普提供参考。
采用自行设计的“公众对 DCT 的认知度在线调查问卷”,于 2022 年 1 月至 3 月进行在线调查,收集参与者的人口统计学特征及对 DCT 的认知度和参与意愿的反应。采用单因素和二项逻辑回归分析影响公众对 DCT 认知度的因素。
共收集到 1380 份有效问卷,公众对 DCT 的认知率为 61.1%。13 个人口统计学特征(年龄、性别、教育程度、职业、工作领域、家庭类型、婚姻状况、城市类型、收入、医疗保险、医疗支出、就医压力、经济压力),均显著影响参与者对 DCT 的认知度合格率(P<0.001)。二项逻辑回归分析表明,教育程度、工作领域、城市类型、医疗保险和医疗支出独立影响参与者对 DCT 的认知率(P<0.001)。52.9%的参与者愿意参加 DCT。“促进医学进步”(54.4%)或“相信医生”(31.1%)是受试者参与 DCT 的最常见原因。
公众对 DCT 的认知度和参与意愿受到受试者人口统计学特征的显著影响。因此,应针对公众的需求,开展 DCT 的宣传和科普工作,服务于公众健康。