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Diabetes mellitus burden among people living with HIV from the Asia-Pacific region.亚太地区 HIV 感染者的糖尿病负担。
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Prevalence and Associated Risk Factors of Hyperglycemia and Diabetes Mellitus Among HIV Positive Patients in Tehran, Iran.伊朗德黑兰HIV阳性患者中高血糖和糖尿病的患病率及相关危险因素
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印度艾滋病毒/艾滋病感染者中特定心血管危险因素及其相关因素的患病率。

Prevalence of Selected Cardiovascular Risk Factors and Their Associated Factors among People Living with HIV/AIDS in India.

作者信息

Sakthivel Manikandanesan, Jayaseelan Venkatachalam, Chinnakali Palanivel, Hamide Abdoul, Surendran Gayathri, Krishnamoorthy Yuvaraj

机构信息

Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

出版信息

Indian J Community Med. 2024 Mar-Apr;49(2):308-315. doi: 10.4103/ijcm.ijcm_583_22. Epub 2024 Mar 7.

DOI:10.4103/ijcm.ijcm_583_22
PMID:38665444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11042137/
Abstract

BACKGROUND

Low- and middle-income countries face the dual problem of infectious and non-infectious diseases. Persons living with HIV/AIDS (PLHIV) are also at risk of cardiovascular diseases. Hence, we did this study to determine the prevalence of cardiovascular risk factors (CVRF) among PLHIV and to find the factors associated with it.

METHODS

We carried out a cross-sectional analytical study among all adults aged ≥18 years registered at a facility-integrated anti-retroviral therapy center in Puducherry, India, from September 2016 to February 2018. After obtaining informed consent, we interviewed the participants to assess physical activity, alcohol, and tobacco use. We measured weight, height, abdominal circumference, and blood pressure, with biochemical investigations such as blood glucose and lipid profile.

RESULTS

Of the total 316 adults PLHIV studied, the most common cardiovascular risk factor found was dyslipidemia (82.7%), followed by inadequate physical activity (74.4%). Other behavioral risk factors studied, such as current tobacco use and current alcohol use, showed a prevalence of 12.8% and 5.4%, respectively, among male participants. The prevalence of hypertension among adult PLHIV studied was 15.8%, and diabetes was 12.3%. In the multivariate analysis, diabetes, and hypertension were significantly associated with age and literacy. Obesity was found to be associated with diabetes and abdominal obesity with dyslipidemia.

CONCLUSION

Dyslipidemia was the most common cardiovascular risk factor, followed by inadequate physical inactivity among PLHIV. Regular screening with blood glucose, blood pressure, and lipid profile, and timely cross-referrals can help in the early detection of CVRF among PLHIV and hence improve their quality of life through appropriate treatment.

摘要

背景

低收入和中等收入国家面临传染病和非传染病的双重问题。艾滋病毒/艾滋病感染者(PLHIV)也有患心血管疾病的风险。因此,我们开展了这项研究,以确定PLHIV中心血管危险因素(CVRF)的患病率,并找出与之相关的因素。

方法

我们于2016年9月至2018年2月在印度本地治里一家综合设施抗逆转录病毒治疗中心登记的所有18岁及以上成年人中进行了一项横断面分析研究。在获得知情同意后,我们对参与者进行访谈,以评估其身体活动、饮酒和吸烟情况。我们测量了体重、身高、腹围和血压,并进行了血糖和血脂谱等生化检查。

结果

在总共316名接受研究的成年PLHIV中,发现最常见的心血管危险因素是血脂异常(82.7%),其次是身体活动不足(74.4%)。所研究的其他行为危险因素,如当前吸烟和当前饮酒,在男性参与者中的患病率分别为12.8%和5.4%。所研究的成年PLHIV中高血压患病率为15.8%,糖尿病患病率为12.3%。在多变量分析中,糖尿病和高血压与年龄和识字率显著相关。发现肥胖与糖尿病相关,腹部肥胖与血脂异常相关。

结论

血脂异常是PLHIV中最常见的心血管危险因素,其次是身体活动不足。定期进行血糖、血压和血脂谱筛查以及及时转诊有助于早期发现PLHIV中的CVRF,从而通过适当治疗改善他们的生活质量。