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2023 年 10 月,世界卫生组织欧洲区域耐多药/利福平耐药结核病治疗药物的供应情况。

Availability of drugs for the treatment of multidrug-resistant/rifampicin-resistant tuberculosis in the World Health Organization European Region, October 2023.

机构信息

German Central Committee against Tuberculosis (DZK), Berlin, Germany.

Independent Consultant & Department of Healthcare Management, Technical University of Berlin, Berlin, Germany.

出版信息

Euro Surveill. 2024 Apr;29(17). doi: 10.2807/1560-7917.ES.2024.29.17.2400211.

Abstract

The BPaLM regimen (bedaquiline, pretomanid, linezolid and moxifloxacin) recently recommended by the World Health Organization offers short, safe, and effective treatment for multidrug-resistant/rifampicin-resistant tuberculosis (TB). In a survey with national TB focal points in 18 central and western European countries to explore barriers for the implementation of BPaLM, only three reported full availability of pretomanid, a necessary component of this regimen. Implementation barriers included financing and procurement. Solutions on national and supranational level are needed to guarantee universal access.

摘要

世界卫生组织最近推荐的 BPaLM 方案(贝达喹啉、普托马尼德、利奈唑胺和莫西沙星)为耐多药/利福平耐药结核病(TB)提供了一种短期、安全和有效的治疗方法。在一项针对 18 个中、西欧国家国家结核病重点机构的调查中,为探索实施 BPaLM 的障碍,只有三个国家报告了普托马尼德的全面供应,这是该方案的必要组成部分。实施障碍包括融资和采购。需要在国家和超国家层面上找到解决方案,以确保普及。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf9c/11063671/cc07ecb0d19d/2400211-f1.jpg

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