Vommaro Francesco, Ciani Giovanni, Cini Chiara, Maccaferri Bruna, Carretta Elisa, Boriani Luca, Martikos Konstantinos, Scarale Antonio, Parciante Antonio, Leggi Lucrezia, Griffoni Cristiana, Gasbarrini Alessandro
Spine Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Department of Programming and Monitoring, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Eur Spine J. 2024 Jun;33(6):2495-2503. doi: 10.1007/s00586-024-08225-6. Epub 2024 Apr 26.
This is a monocentric retrospective controlled study that compares the safety and efficacy of posterior minimally invasive surgery (MISS) to standard posterior spinal fusion (PSF) surgery in adolescent idiopathic scoliosis (AIS).
We retrospectively collected 111 patients with Lenke type 1-6 AIS who were treated with MIS (n = 47) or PSF (n = 64) between February 2019 and January 2021 with a 2-year clinical and radiological follow-up. MIS technique was applied via two midline noncontiguous skin incisions ranging from 3 to 7 cm in length, so we obtained the arthrodesis only in the exposed tract, passing the rods below the fascia, avoiding the complete muscular sparing. Values of Cobb angles degrees were collected to study the correction rate of the structural major curve. Postoperative AP direct radiography and preoperative AP direct radiography were compared with the last follow-up examination. Operative time, preoperative hemoglobin (Hb) and second postoperative day Hb, full length of hospitalization, time to achieve verticalization and time to remove the drainage were recorded. NRS medium score was assessed immediately after surgery and during the whole postoperative rehabilitation treatment to estimate pain reduction. Complications were collected postoperatively and throughout the whole follow-up period.
There was no significant difference between the two groups in terms of radiographic and clinical features. The correction rates of the structural curve resulted to be not significantly different between MISS and PSF (64.6 ± 11.7 vs 60.9 ± 13.2, p = 0.1292) as well as for the correction rate of the secondary curve between the two compared techniques (59.1 ± 13.2 vs 59.2 ± 12.4, p = 0.9865). The two groups had comparable operative time (210 min vs 215 min). The MIS group had a significantly lower reduction of postoperative Hb in comparison with PSF group (2.8 ± 1.3 mg/dl vs 4.3 ± 1.5 mg/dl, p < 0.0001). The postoperative NRS score was lower in MIS group (1.9 ± 0.8 vs 3.3 ± 1.3). PSF group was observed to have a significantly longer period of hospitalization than MIS (5.2 ± 1.4 days vs 6.3 ± 2.9 days, p = 0.206). Complications were more frequent in PSF group rather than in MFS group.
MISS is a safe and capable alternative to PSF for AIS patients with curves < 70°, with analogue capacity of scoliosis correction and same operative time and with advantages in blood loss, length of stay and postoperative pain.
本研究为单中心回顾性对照研究,旨在比较青少年特发性脊柱侧凸(AIS)患者行后路微创手术(MISS)与标准后路脊柱融合术(PSF)的安全性和有效性。
我们回顾性收集了2019年2月至2021年1月期间接受MIS(n = 47)或PSF(n = 64)治疗的111例Lenke 1-6型AIS患者,并进行了为期2年的临床和影像学随访。MIS技术通过两个长度为3至7厘米的中线不连续皮肤切口应用,因此我们仅在暴露区域获得融合,将棒置于筋膜下方,避免完全保留肌肉。收集Cobb角度数的值以研究结构性主曲线的矫正率。将术后前后位直接X线片与术前前后位直接X线片与最后一次随访检查进行比较。记录手术时间、术前血红蛋白(Hb)和术后第二天Hb、住院总时长、达到垂直化的时间和拔除引流管的时间。术后立即及整个术后康复治疗期间评估NRS中度评分以估计疼痛减轻情况。术后及整个随访期间收集并发症情况。
两组在影像学和临床特征方面无显著差异。MISS和PSF之间结构性曲线的矫正率无显著差异(64.6±11.7 vs 60.9±13.2,p = 0.1292),两种比较技术之间的次要曲线矫正率也无显著差异(59.1±13.2 vs 59.2±12.4,p = 0.9865)。两组手术时间相当(210分钟 vs 215分钟)。与PSF组相比,MIS组术后Hb降低显著更低(2.8±1.3mg/dl vs 4.3±1.5mg/dl,p < 0.0001)。MIS组术后NRS评分更低(1.9±0.8 vs 3.3±1.3)。观察到PSF组住院时间明显长于MIS组(5.2±1.4天 vs 6.3±2.9天,p = 0.206)。PSF组并发症比MFS组更频繁。
对于曲线<70°的AIS患者,MISS是PSF的一种安全且有效的替代方法,具有类似的脊柱侧凸矫正能力、相同的手术时间,并且在失血、住院时间和术后疼痛方面具有优势。