Programa de Transtorno Bipolar, Laboratório de Psiquiatria Molecular, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Programa de Pós-Graduação em Psiquiatria, Departamento de Psiquiatria, UFRGS, Porto Alegre, RS, Brazil. Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, ON, Canada. Alliance Research Group, UFRGS, Porto Alegre, RS, Brazil.
Alliance Research Group, UFRGS, Porto Alegre, RS, Brazil.
Braz J Psychiatry. 2024;46:e20233363. doi: 10.47626/1516-4446-2023-3363. Epub 2024 Apr 26.
From a preventive perspective, this study reviewed the literature on protective factors against depressive symptoms in high-risk children and adolescents.
We conducted a thorough search of the PubMed, APA, EMCare, and Embase databases for studies published between 1946 and August 25, 2023. We included only longitudinal studies that analyzed protective factors for depressive symptoms in high-risk children or adolescents, excluding cross-sectional studies, reviews, and pre-clinical studies.
A total of 29 studies with 62,405 participants were analyzed and 38 protective factors were identified. Positive individual characteristics, family factors, peer relationships, school-related aspects, neighborhood characteristics, and intrinsic religiosity were associated with improved depression outcomes.
These findings have important implications for preventive strategies in this population. Addressing protective factors can help prevent depression and enhance lifetime mental health.
从预防的角度出发，本研究对高危儿童和青少年抑郁症状的保护因素相关文献进行了综述。
我们全面检索了 PubMed、APA、EMCare 和 Embase 数据库中 1946 年 8 月 25 日至 2023 年 8 月 25 日期间发表的研究。我们仅纳入了分析高危儿童或青少年抑郁症状保护因素的纵向研究，排除了横断面研究、综述和临床前研究。
共分析了 29 项研究，涉及 62405 名参与者，确定了 38 个保护因素。积极的个体特征、家庭因素、同伴关系、与学校相关的方面、邻里特征和内在宗教信仰与改善抑郁结局相关。
这些发现对该人群的预防策略具有重要意义。针对保护因素进行干预可能有助于预防抑郁的发生，提升个体终生的心理健康水平。
