Mickleson K N, Dixon M W, Hill P J, Bluck R, Eales M, Rutherford J, Yakas J, Trent R J
N Z Med J. 1985 Dec 11;98(792):1036-8.
DNA mapping of the alpha globin gene cluster in cord blood from Polynesians has shown an increased frequency of alpha thalassaemia and triplicated alpha genes. Reduced levels of haemoglobin, mean corpuscular haemoglobin or mean corpuscular volume in these neonates may indicate alpha thalassaemia. Recognition of this will avoid unnecessary haematological investigations and iron supplementation.
对来自波利尼西亚人的脐带血中α珠蛋白基因簇进行的DNA图谱分析显示,α地中海贫血和α基因三倍体的频率增加。这些新生儿血红蛋白、平均红细胞血红蛋白或平均红细胞体积水平降低可能表明存在α地中海贫血。认识到这一点将避免不必要的血液学检查和铁补充。