新生儿脾脏体积在不同疟疾流行状况下有所不同。
Newborn splenic volumes vary under different malaria endemic conditions.
作者信息
Corkill J A, Brabin B J, MacGregor D F, Alpers M P, Milner R D
机构信息
Department of Paediatrics, University of Sheffield, Children's Hospital.
出版信息
Arch Dis Child. 1989 Apr;64(4):541-5. doi: 10.1136/adc.64.4.541.
Abstract
Ultrasound was used to measure newborn splenic dimensions and calculate the volumes in a malarious and a non-malarious region of Papua New Guinea. The median splenic volume of infants born in Madang, where malaria transmission is high throughout the year, was 5.2 cm3/kg, while that of infants born in Goroka, where malaria is not endemic, was 2.6 cm3/kg. The cause of this difference is unknown, but possible explanations include fetal exposure to malaria antigens in utero and the high incidence of inherited red cell disorders in the malarious regions of Papua New Guinea.
摘要
在巴布亚新几内亚的一个疟疾流行地区和一个非疟疾流行地区，使用超声测量新生儿脾脏尺寸并计算其体积。在马当出生的婴儿，全年疟疾传播率很高，其脾脏体积中位数为5.2立方厘米/千克，而在戈罗卡出生的婴儿，该地无疟疾流行，其脾脏体积中位数为2.6立方厘米/千克。这种差异的原因尚不清楚，但可能的解释包括胎儿在子宫内接触疟疾抗原，以及巴布亚新几内亚疟疾流行地区遗传性红细胞疾病的高发病率。
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