Ossanna Riccardo, Ghazanfar Tehrani Sara, Dallatana Alessia, Khabouri Sima, Veronese Sheila, Sbarbati Andrea, Goisis Mario
Department of Neuroscience, Biomedicine, and Movement, Section of Anatomy and Histology, University of Verona, 37134 Verona, Italy.
Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37134 Verona, Italy.
J Clin Med. 2024 Apr 19;13(8):2387. doi: 10.3390/jcm13082387.
Non-surgical rhinoplasty is one of the best choices in mild cases of the saddle nose, and it represents a solution for the aesthetical amelioration of facial deformity; nevertheless, in most critical cases, surgical intervention is still required. This study reports the experience and results of a single facial plastic surgeon (M.G.) using a non-surgical technique for the correction of saddle noses in a large cohort of patients. This retrospective study assesses all patients injected from January 2017 through October 2023 in private clinics in Milan (Italy), London (UK), and Dubai (UAE). All patients were followed up for 12 months. The harvested adipose tissues were processed with different systems and with or without acoustic wave therapy (AWT). The extracted products have been characterized in terms of cellular yield and cell growth. Ninety-seven patients were injected with adipose-derived products or hyaluronic acid (HA). Patients were followed up for 12 months, and satisfaction data were analyzed. The stem cells obtained from the patients who previously received AWT displayed a statistically higher cell growth ability in comparison with those of the cells derived from patients who did not receive AWT. The evolution of patient satisfaction during the time for each group of treatment was investigated, and cellular treatments show the best maintenance of patient satisfaction over time. Dermgraft and AWT approaches resulted in the highest patient satisfaction for the non-surgical correction of the saddle nose deformity.
非手术隆鼻是轻度鞍鼻病例的最佳选择之一,它为面部畸形的美学改善提供了一种解决方案;然而,在大多数严重病例中,仍需要手术干预。本研究报告了一位面部整形外科医生(M.G.)在一大群患者中使用非手术技术矫正鞍鼻的经验和结果。这项回顾性研究评估了2017年1月至2023年10月期间在意大利米兰、英国伦敦和阿联酋迪拜的私人诊所接受注射的所有患者。所有患者均接受了12个月的随访。采集的脂肪组织采用不同系统进行处理,并使用或不使用声波疗法(AWT)。提取的产品已根据细胞产量和细胞生长进行了表征。97名患者接受了脂肪衍生产品或透明质酸(HA)注射。对患者进行了12个月的随访,并对满意度数据进行了分析。与未接受AWT的患者来源的细胞相比,先前接受AWT的患者获得的干细胞显示出统计学上更高的细胞生长能力。研究了每组治疗期间患者满意度的变化情况,细胞治疗随着时间推移显示出对患者满意度的最佳维持效果。Dermgraft和AWT方法在鞍鼻畸形的非手术矫正中导致了最高的患者满意度。