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使用 3D 打印的模体插件评估在 Leksell Gamma Knife 剂量学中用于确定射野输出因子的辐射探测器。

Evaluation of radiation detectors for the determination of field output factors in Leksell Gamma Knife dosimetry using 3D printed phantom inserts.

机构信息

Radiation Oncology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Queensland 4102, Australia.

Radiation Oncology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Queensland 4102, Australia.

出版信息

Phys Med. 2024 May;121:103370. doi: 10.1016/j.ejmp.2024.103370. Epub 2024 Apr 26.

DOI:10.1016/j.ejmp.2024.103370
PMID:38677196
Abstract

The Leksell Gamma Knife® Perfexion™ and Icon™ have a unique geometry, containing 192 Co sources with collimation for field sizes of 4 mm, 8 mm, and 16 mm. 4 mm and 8 mm collimated fields lack lateral charged particle equilibrium, so accurate field output factors are essential. This study performs field output factor measurements for the microDiamond, microSilicon, and RAZOR™ Nano detectors. 3D printed inserts for the spherical Solid Water® Phantom were fabricated for microDiamond detector, the microSilicon unshielded diode and the RAZOR™ Nano micro-ionisation chamber. Detectors were moved iteratively to identify the peak detector signal for each collimator, representing the effective point of measurement of the chamber. In addition, field output correction factors were calculated for each detector relative to vendor supplied Monte Carlo simulated field output factors and field output factors measured with a W2 scintillator. All field output factors where within 1.1 % for the 4 mm collimator and within 2.3 % for the 8 mm collimator. The 3D printed phantom inserts were suitable for routine measurements if the user identifies the effective point of measurement, and ensures a reproducible setup by marking the rotational alignment of the cylindrical print. Measurements with the microDiamond and microSilicon can be performed faster compared to the RAZOR™ Nano due to differences in the signal to noise ratio. All detectors are suitable for field output factor measurements for the Leksell Gamma Knife® Perfexion™ and Icon™.

摘要

Leksell Gamma Knife® Perfexion™ 和 Icon™ 具有独特的几何形状,包含 192 个钴源,适用于 4mm、8mm 和 16mm 的准直器。4mm 和 8mm 准直器场缺乏侧向带电粒子平衡,因此准确的场输出因子至关重要。本研究对 microDiamond、microSilicon 和 RAZOR™ Nano 探测器进行了场输出因子测量。为 microDiamond 探测器、microSilicon 无屏蔽二极管和 RAZOR™ Nano 微电离室制造了用于 Solid Water® Phantom 的 3D 打印插件。探测器被反复移动,以识别每个准直器的峰值探测器信号,代表腔的有效测量点。此外,还计算了每个探测器相对于供应商提供的蒙特卡罗模拟场输出因子和用 W2 闪烁体测量的场输出因子的场输出校正因子。对于 4mm 准直器,所有场输出因子均在 1.1%以内,对于 8mm 准直器,所有场输出因子均在 2.3%以内。如果用户确定有效测量点,并通过标记圆柱形打印的旋转对准来确保可重复的设置,则 3D 打印的幻影插件适合常规测量。由于信噪比的差异,microDiamond 和 microSilicon 的测量速度可以比 RAZOR™ Nano 更快。所有探测器均适用于 Leksell Gamma Knife® Perfexion™ 和 Icon™ 的场输出因子测量。

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