Cluxton R J, Hunter R H, Reed R C
Am J Hosp Pharm. 1979 Sep;36(9):1215-8.
The usefulness of five drug information services in obtaining bioavailability data from journal literature is compared. The deHAEN Drugs in Use system, the Iowa Drug Information Service (IDIS), Index Medicus, MEDLINE and International Pharmaceutical Abstracts (IPA), each for a 10-year period, were searched for citations on bioavailability studies on the oral dosage forms of acetaminophen, lithium carbonate, phenytoin, nitrofurantoin and theophylline. Both quantity of references indexed and quality of data were considered. No significant difference was found in the mean value scores for the five services. Index Medicus provided 79 citations but required 7.7 hours of search time. MEDLINE yielded 62 citations but required only 1.1 hours to search. IPA, IDIS and deHaen had lower numbers of citations and intermediate search times. IPA, deHaen and Index Medicus all cited unique articles, with 11%, 7% and 3%, respectively. Index Medicus had the lowest percent of articles duplicated by two or more services (49%). The most comprehensive serch with the fewest duplicate citations would be obtained from searching deHaen's Drugs in Use, IPA and Index Medicus.
比较了五种药物信息服务在从期刊文献中获取生物利用度数据方面的效用。对德汉药物使用系统、爱荷华药物信息服务（IDIS）、《医学索引》、医学文献数据库（MEDLINE）和《国际药学文摘》（IPA）进行了为期10年的检索，以查找关于对乙酰氨基酚、碳酸锂、苯妥英、呋喃妥因和茶碱口服剂型生物利用度研究的文献引用。同时考虑了索引文献的数量和数据质量。这五种服务的平均值分数没有显著差异。《医学索引》提供了79条引用，但需要7.7小时的检索时间。医学文献数据库检索到62条引用，但仅需1.1小时。IPA、IDIS和德汉的引用数量较少，检索时间居中。IPA、德汉和《医学索引》都引用了独特的文章，分别为11%、7%和3%。《医学索引》中被两种或更多服务重复引用的文章比例最低（49%）。通过检索德汉的药物使用系统、IPA和《医学索引》可以获得引用重复最少且最全面的检索结果。
