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临床试验中肿瘤患者治疗带来的药品成本节约。

Pharmaceutical cost savings from the treatment of oncology patients in clinical trials.

作者信息

Gómez Mediavilla Borja, Lanza-León Paloma, Martínez Callejo Virginia, Cantarero-Prieto David, Lanza Postigo María, Salcedo Lambea Matilde, Blanco Mesonero Yolanda, Ochagavia Sufrategui María, Durán Ignacio, Sarabia Cobo Carmen María

机构信息

Medical Oncology and Nanovaccines Research Gruop, Instituto de Investigación Valdecilla-IDIVAL, Santander, Spain.

Departamento de Economía, Universidad de Cantabria, Santander, Spain; Health Economics Research Group, Valdecilla Biomedical Institute Research - IDIVAL, Santander, Spain.

出版信息

Biomed J. 2024 Apr 27;48(2):100742. doi: 10.1016/j.bj.2024.100742.

DOI:10.1016/j.bj.2024.100742
PMID:38679197
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12049827/
Abstract

OBJECTIVE

The aim of this study was twofold: to assess the annual pharmaceutical savings associated with the treatment of cancer patients at Marqués de Valdecilla University Hospital and to estimate the cost of innovative antineoplastic therapies that patients receive as experimental treatment, both during clinical trials throughout 2020.

MATERIAL AND METHODS

An observational and financial analysis of the drug cost related to clinical trials was applied. Direct cost savings to the Regional Health System of Cantabria and the cost of innovative therapies used as an experimental treatment in clinical trials were quantified.

RESULTS

This study includes 38 clinical trials with a sample of 101 patients. The clinical trials analyzed provide a total cost savings of €603,350.21 and an average cost saving of €6630.22 per patient. Furthermore, the total investment amounts to €789,892.67, with an average investment of €15,488.09 per patient.

CONCLUSIONS

Clinical trials are essential for the advancement of science. Furthermore, clinical trials can be a significant source of income for both hospitals and Regional Health Systems, contributing to their financial sustainability.

摘要

目的

本研究有两个目的:评估与马尔克斯·德·巴尔德西利亚大学医院癌症患者治疗相关的年度药品节省情况,并估算2020年全年临床试验期间患者作为试验性治疗接受的创新抗肿瘤疗法的费用。

材料与方法

对与临床试验相关的药品成本进行观察性和财务分析。量化了坎塔布里亚地区卫生系统的直接成本节省以及在临床试验中用作试验性治疗的创新疗法的成本。

结果

本研究包括38项临床试验,样本为101名患者。分析的临床试验总共节省成本603,350.21欧元,每位患者平均节省成本6630.22欧元。此外,总投资为789,892.67欧元,每位患者平均投资15,488.09欧元。

结论

临床试验对科学进步至关重要。此外,临床试验可以成为医院和地区卫生系统的重要收入来源,有助于其财务可持续性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/38ea34ae8a92/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/4161617acc73/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/9589818be99e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/7fd0f9b6458b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/38ea34ae8a92/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/4161617acc73/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/9589818be99e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/7fd0f9b6458b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d690/12049827/38ea34ae8a92/gr4.jpg

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Clinical trials and drug cost savings for Italian health service.意大利卫生服务的临床试验和药品成本节约。
BMC Health Serv Res. 2020 Nov 26;20(1):1089. doi: 10.1186/s12913-020-05928-6.
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Importance of proper conduct of clinical trials.正确开展临床试验的重要性。
Br J Anaesth. 2021 Feb;126(2):354-356. doi: 10.1016/j.bja.2020.09.030. Epub 2020 Oct 26.
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Drug cost savings in phase III hematological oncology clinical trials in a university hospital.在一所大学附属医院的 III 期血液肿瘤学临床试验中节省药物成本。
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Are cancer patients better off if they participate in clinical trials? A mixed methods study.癌症患者参与临床试验是否获益更多?一项混合方法研究。
BMC Cancer. 2020 May 8;20(1):401. doi: 10.1186/s12885-020-06916-z.
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Weighing Costs and Benefits in the Economics of Cancer Care.权衡癌症护理经济学中的成本与收益。
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