抗胆碱能药术前用药后胃内容物的容量及pH值

Volume and pH of gastric contents following anticholinergic premedication.

作者信息

Mirakhur R K, Reid J, Elliott J

出版信息

Anaesthesia. 1979 May;34(5):453-7. doi: 10.1111/j.1365-2044.1979.tb06323.x.

DOI:10.1111/j.1365-2044.1979.tb06323.x

Abstract

The effects of anticholinergic premedication with 1.0 mg atropine, 0.5 mg hyoscine and 0.2 mg glycopyrronium on volume and pH of gastric contents were studied and compared with a group receiving no anticholinergic premedication. The antisialogogue effects were also compared. Though the groups receiving atropine and glycopyrronium had the lowest mean aspirated volume and the highest mean pH respectively there was no essential difference between the various groups receiving anticholinergic premedication. However, the pH values were above 2.5 in the majority of these patients in comparison with the control group. The antisialogogue effects of the three anticholinergic drugs were similar.

摘要

研究了1.0毫克阿托品、0.5毫克东莨菪碱和0.2毫克格隆溴铵进行抗胆碱能术前用药对胃内容物体积和pH值的影响，并与未接受抗胆碱能术前用药的一组进行了比较。还比较了它们的抑制唾液分泌作用。尽管接受阿托品和格隆溴铵的组分别具有最低的平均吸出量和最高的平均pH值，但接受抗胆碱能术前用药的各个组之间没有本质区别。然而，与对照组相比，这些患者中的大多数pH值高于2.5。这三种抗胆碱能药物的抑制唾液分泌作用相似。