Hung T D, Lam N N
Le Huu Trac National Burn Hospital & Viet Nam Medical Military University, Hanoi, Viet Nam.
Ann Burns Fire Disasters. 2023 Dec 31;36(4):271-275. eCollection 2023 Dec.
The aim of this study was to investigate factors independently affecting outcomes of post-burn ARDS patients at the time of ARDS onset. A prospective study was conducted on 66 patients with ARDS, treated in the ICU at the Le Huu Trac National Burns Hospital in Hanoi, Viet Nam, from 2014 to 2017. Patients were divided into a survivor and non-survivor group. Demographic criteria, burn severity, inhalation injury, clinical and subclinical features at ARDS onset were compared between the two groups. The results showed that overall mortality of ARDS patients was 62.12%. Logistic regression analysis indicated that at the time of ARDS onset, serum lactate level (OR=6.71), blood platelet count (OR=.99), static lung compliance (OR=.73) and driving pressure (OR=1.69) were independent risk factors for death, while patients' demographics, burn severity and ARDS severity did not significantly affect the mortality rate.
本研究的目的是调查在急性呼吸窘迫综合征（ARDS）发病时独立影响烧伤后ARDS患者预后的因素。2014年至2017年，对越南河内黎友德国家烧伤医院重症监护病房收治的66例ARDS患者进行了一项前瞻性研究。患者被分为存活组和非存活组。比较了两组患者的人口统计学标准、烧伤严重程度、吸入性损伤、ARDS发病时的临床和亚临床特征。结果显示，ARDS患者的总体死亡率为62.12%。逻辑回归分析表明，在ARDS发病时，血清乳酸水平（OR=6.71）、血小板计数（OR=0.99）、静态肺顺应性（OR=0.73）和驱动压（OR=1.69）是死亡的独立危险因素，而患者的人口统计学特征、烧伤严重程度和ARDS严重程度对死亡率没有显著影响。
