Melhem Yara, Khattab Seham, Al-Janabi Moatasem Hussein, Saeid Hussein, Ahmad Issa, Hasan Fouz
Department of Dermatology, Tishreen University Hospital, Lattakia, Syria.
Department of Pathology, Cancer Research Center, Tishreen University Hospital, Lattakia, Syria.
Oxf Med Case Reports. 2024 Apr 25;2024(4):omae035. doi: 10.1093/omcr/omae035. eCollection 2024 Apr.
Immunosuppressed individuals face a significantly elevated risk of developing aggressive cutaneous malignancies, often surpassing the aggressiveness observed in immunocompetent counterparts. Our patient exhibited several risk factors associated with melanoma development in renal recipients, including skin type, sun exposure, and the duration of immunosuppression. The determination of staging holds paramount importance as it directly influences both prognosis and subsequent management. It is crucial to handle suspected lesions with caution in these patients to facilitate early melanoma detection and enhance overall prognosis.
免疫抑制个体发生侵袭性皮肤恶性肿瘤的风险显著升高,其侵袭性往往超过免疫功能正常者。我们的患者表现出了肾移植受者中与黑色素瘤发生相关的几个风险因素,包括皮肤类型、阳光暴露和免疫抑制持续时间。分期的确定至关重要,因为它直接影响预后和后续治疗。在这些患者中谨慎处理可疑病变对于促进黑色素瘤的早期发现和改善总体预后至关重要。