Cheng Qi, Zhou Xian, Chen Shu
Infectious Diseases, Huashan Hospital, Shanghai, CHN.
Cureus. 2024 Mar 28;16(3):e57146. doi: 10.7759/cureus.57146. eCollection 2024 Mar.
Lactic acidosis is a rare but severe complication of B-cell lymphoma, often associated with rapid disease progression and poor prognosis. We present a case of a 60-year-old male admitted with fever, splenomegaly, hemophagocytic tendencies, and lactic acidosis. The patient underwent several dialysis sessions before bone marrow flow cytometry finally confirmed B-cell lymphoma. However, hyperlactatemia persisted and recurred. The case underscores the challenges in diagnosing lymphomas with atypical presentations and emphasizes the critical role of timely bone marrow analysis. Additionally, the paper discusses the association between B-cell lymphoma and lactic acidosis, highlighting the importance of early recognition and intervention.
乳酸酸中毒是B细胞淋巴瘤一种罕见但严重的并发症,常与疾病快速进展和预后不良相关。我们报告一例60岁男性患者,因发热、脾肿大、噬血细胞倾向和乳酸酸中毒入院。该患者在骨髓流式细胞术最终确诊为B细胞淋巴瘤之前接受了多次透析治疗。然而,高乳酸血症持续存在且复发。该病例凸显了诊断非典型表现淋巴瘤的挑战,并强调了及时进行骨髓分析的关键作用。此外,本文讨论了B细胞淋巴瘤与乳酸酸中毒之间的关联,强调了早期识别和干预的重要性。