调节对人晶状体几何参数的影响：一项系统评价和荟萃分析。

Effects of accommodation on geometrical parameters of human lens: A systematic review and meta-analysis.

作者信息

Zhang Guanghong, Jiang Jun, Wei Qian, Qu Chao

机构信息

Department of Ophthalmology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 2006, Xiyuan Ave West Hi-Tech Zone, Chengdu, CN 611731, China.

School of Medicine, University of Electronic Science and Technology of China, No. 2006, Xiyuan Ave West Hi-Tech Zone, Chengdu, CN 611731, China.

出版信息

Heliyon. 2024 Apr 16;10(8):e29298. doi: 10.1016/j.heliyon.2024.e29298. eCollection 2024 Apr 30.

DOI:10.1016/j.heliyon.2024.e29298

PMID:38681553

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11053204/

Abstract

PURPOSE

To investigate the effects of accommodation on the geometrical parameters of human lens.

METHODS

Eight databases from inception to November 2023 were used for the literature search: CNKI, CBM, VIP, Wan-Fang, PubMed, Web of Science, EMBASE, and the Cochrane Library. The Methodological Index for Non-randomized Studies was used to assess the risk of bias. The PRISMA were followed and the following outcomes were taken into consideration: lens diameter (LD), lens thickness (LT), anterior curvature radius (ACR), posterior curvature radius (PCR), lens center position (LCP), and total cross-sectional area (TCSA). This systematic review was registered on an international platform for registered systematic reviews and meta-analysis (INPLASY202260085).

RESULTS

A total of 19 studies were included. LT increased by 0.04 mm/D (18 studies; 95% confidence interval [CI], 0.03-0.06; = 96.6%; < 0.001). At the same time, LD, ACR, and PCR decreased by 0.06 mm/D (6 studies; 95%CI, -0.07-0.05; = 50.1%; < 0.001), 0.53 mm/D (8 studies; 95%CI, -0.64-0.41; = 96.5%; < 0.001), and 0.14 mm/D (9 studies; 95%CI, -0.19-0.09; = 94.7%; < 0.001) during accommodation, respectively. Moreover, LCP shifted forward by 0.01 mm/D (3 studies; 95%CI, -0.02-0.00; = 0.0%; < 0.001), and TCSA by 0.58 mm/D (2 studies; 95%CI, 0.41-1.57; = 97.0%; = 0.457) during accommodation.

CONCLUSIONS

Changes in LT, LD, ACR, PCR and LCP supported Helmholtz's theory. Different apparatuses or measurement methods influenced the measurement of lens geometrical parameters.

摘要

目的

研究调节对人晶状体几何参数的影响。

方法

检索了从建库至2023年11月的8个数据库：中国知网、中国生物医学文献数据库、维普资讯网、万方数据、PubMed、科学引文索引、荷兰医学文摘数据库和考克兰图书馆。采用非随机研究方法学指标评估偏倚风险。遵循系统评价和Meta分析的首选报告项目（PRISMA），并考虑以下结果：晶状体直径（LD）、晶状体厚度（LT）、前曲率半径（ACR）、后曲率半径（PCR）、晶状体中心位置（LCP）和总横截面积（TCSA）。该系统评价已在国际注册系统评价和Meta分析平台（INPLASY202260085）上注册。

结果

共纳入19项研究。调节时，LT以0.04 mm/D的速度增加（18项研究；95%置信区间[CI]，0.03 - 0.06；I² = 96.6%；P < 0.001）。同时，LD、ACR和PCR分别以0.06 mm/D（6项研究；95%CI， - 0.07 - 0.05；I² = 50.1%；P < 0.001）、0.53 mm/D（8项研究；95%CI， - 0.64 - 0.41；I² = 96.5%；P < 0.001）和0.14 mm/D（9项研究；95%CI， - 0.19 - 0.09；I² = 94.7%；P < 0.001）的速度减小。此外，调节时LCP向前移动0.01 mm/D（3项研究；95%CI， - 0.02 - 0.00；I² = 0.0%；P < 0.001），TCSA以0.58 mm/D的速度增加（2项研究；95%CI，0.41 - 1.57；I² = 97.0%；P = 0.457）。