Furuichi Shuro, Namba Yoshifumi, Sugimoto Yoshihisa, Oishi Tomohiro, Mitani Shigeru
Department of Bone and Joint Surgery, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Department of Traumatology and Spine Surgery, Kawasaki Medical School, Kurashiki, Okayama, Japan.
J Orthop Case Rep. 2024 Apr;14(4):73-77. doi: 10.13107/jocr.2024.v14.i04.4364.
Recently, Serratia marcescens was reported to cause nosocomial infections.
In this study, we report a case of S. marcescens infection occurring after total knee arthroplasty (TKA) in a 72-year-old woman. The patient had undergone TKA for knee osteoarthritis. She had a past medical history of diabetes mellitus, for which she was receiving cefazolin sodium. Six days after surgery, redness and effusion were observed in the wound, and post-operative infection was suspected. Thus, the patient was treated with linezolid, clindamycin, and tazobactam/piperacillin hydrate post-operatively. Twelve days after TKA, reinfection was suspected; hence, washing and debridement were repeated.
In this case, remission of S. marcescens infection was achieved without the need to remove the implant by cleaning, debridement, and the use of sensitive antimicrobial agents.
最近,有报道称粘质沙雷氏菌可引起医院感染。
在本研究中,我们报告了一例72岁女性在全膝关节置换术(TKA)后发生粘质沙雷氏菌感染的病例。该患者因膝关节骨关节炎接受了TKA手术。她有糖尿病病史,正在接受头孢唑林钠治疗。术后第六天,伤口出现红肿和积液,怀疑发生术后感染。因此,患者术后接受了利奈唑胺、克林霉素和他唑巴坦/哌拉西林三水合物治疗。TKA术后12天,怀疑再次感染;因此,再次进行了冲洗和清创。
在本病例中,通过清洁、清创和使用敏感抗菌药物,无需取出植入物即可实现粘质沙雷氏菌感染的缓解。