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妊娠期间的1型发作性睡病:一例病例报告及文献综述

Type 1 Narcolepsy in Pregnancy: A Case Report and Review of Literature.

作者信息

Yuabov Asnat, Kilinsky Alexandra, El Kady Dina

机构信息

New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York.

Department of Pediatrics, University of Colorado, School of Medicine, Pediatric Hospitalist Children's Hospital Colorado, Aurora, Colorado.

出版信息

AJP Rep. 2024 Apr 26;14(2):e120-e123. doi: 10.1055/a-2297-4583. eCollection 2024 Apr.

Abstract

Type 1 narcolepsy (with cataplexy) is a rare disorder affecting the central nervous system and is characterized by the inability to control sleep-wake cycles. There is a paucity of data regarding management during pregnancy.  This is a 23-year-old primigravida with narcolepsy and cataplexy, treated with methylphenidate in the third trimester, resulting in an improvement of episodes of cataplexy. A review of the literature reveals information regarding options for medical management and the mode of delivery for these women.  Type 1 narcolepsy can be treated with medications after consideration of risks and benefits. For patients who are symptomatic at the time of birth, cesarean section may be the preferred mode of delivery in women with type 1 narcolepsy.

摘要

1型发作性睡病(伴猝倒)是一种影响中枢神经系统的罕见疾病,其特征是无法控制睡眠 - 觉醒周期。关于孕期管理的数据很少。 这是一名患有发作性睡病和猝倒的23岁初产妇,在孕晚期接受了哌甲酯治疗,猝倒发作有所改善。文献综述揭示了这些女性的药物治疗选择和分娩方式的相关信息。 1型发作性睡病在考虑风险和益处后可进行药物治疗。对于出生时出现症状的患者,剖宫产可能是1型发作性睡病女性的首选分娩方式。

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