Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Magn Reson Imaging. 2024 Sep;111:103-112. doi: 10.1016/j.mri.2024.04.030. Epub 2024 Apr 27.
For patients with complete breast resection, conventional contrast-enhanced T1-weighted imaging (CE-T1WI) with frequency-selective spectral attenuated inversion recovery (SPAIR) provides limited fat suppression on the postoperative side due to the uneven skin surface, inhomogeneous tissue environment, and frequency-selective feature of the SPAIR scheme, leading to difficulties in precise diagnosis. This study aimed to investigate the image quality and performance of the Dixon method compared with SPAIR in breast high-resolution CE-T1WI for mastectomy patients.
Sixty female patients who had not performed any breast surgeries were randomly selected retrospectively as the control group. Postmastectomy female patients were enrolled to undergone high-resolution CE-T1WI with SPAIR and Dixon breast scans. Subjective scores were rated using a 5-point scale. Objective parameters, including contrast-to-noise ratio (CNR), edge sharpness, and signal uniformity were measured and calculated. The Wilcoxon rank-sum test and Kappa statistic were used.
A total of 114 consecutive postmastectomy patients were included. Subjective scores of T1WI-SPAIR in the control group were all significantly better than those with SPAIR on the postoperative side of mastectomy patients (P < 0.01). Dixon outperformed SPAIR with significantly better subjective scores in regards to uniformity and degree of fat-suppression, anatomical structures depiction, lesion conspicuity, and axillary visibility (p < 0.05) in both post- and non-operative sides and bilateral axillary areas through the paired comparison. The objective parameters of Dixon were significantly better than those of SPAIR.
The Dixon method provided better image uniformity and higher fat suppression efficiency, and showed significant advantages in delineating the anatomical structures, with better axillary and lesion visibilities, especially on the completely removed breast side.
对于接受全乳切除术的患者，由于皮肤表面不均匀、组织环境不均匀以及 SPAIR 方案的频率选择特性，常规的频率选择谱衰减反转恢复（SPAIR）增强 T1 加权成像（CE-T1WI）在术后侧提供的脂肪抑制效果有限，导致精确诊断困难。本研究旨在探讨 Dixon 方法与 SPAIR 在全乳切除术后患者乳腺高分辨率 CE-T1WI 中的图像质量和性能。
回顾性随机选择 60 名未接受过任何乳腺手术的女性作为对照组。招募全乳切除术后女性患者进行 SPAIR 和 Dixon 乳腺扫描的高分辨率 CE-T1WI。使用 5 分制对主观评分进行评分。测量和计算对比噪声比（CNR）、边缘锐利度和信号均匀性等客观参数。使用 Wilcoxon 秩和检验和 Kappa 统计。
共纳入 114 例连续全乳切除术后患者。对照组 T1WI-SPAIR 的主观评分均明显优于全乳切除术后患者 SPAIR 的术后侧（P<0.01）。与 SPAIR 相比，Dixon 在均匀性和脂肪抑制程度、解剖结构描绘、病灶显示和腋窝可视性方面的主观评分均显著更好（p<0.05），双侧腋窝区通过配对比较。Dixon 的客观参数明显优于 SPAIR。
Dixon 法提供了更好的图像均匀性和更高的脂肪抑制效率，在描绘解剖结构方面具有明显优势，腋窝和病灶的可视性更好，特别是在完全切除的乳房侧。
