Enenche Augustine A, Kweki Anthony G, Aiwuyo Henry O, Akinti Oluwasegun M, Nevolina Anna, Perry Jamal C, Ayinalem Yonael, Osarenkhoe John O, Ukenenye Emmanuel, Poluyi Charles O, Ibrahim Aishatu O
Internal Medicine, Jos University Teaching Hospital, Jos, NGA.
Internal Medicine/Cardiology, Dalhatu Araf Specialist Hospital, Lafia, NGA.
Cureus. 2024 Mar 31;16(3):e57313. doi: 10.7759/cureus.57313. eCollection 2024 Mar.
Liver cirrhosis (LC) is a common complication of chronic liver disease. Its prevalence has increased markedly over the last few years. With liver cirrhosis comes cardiovascular morbidity and mortality. It is important that the detection of the abnormalities by echocardiography be given priority, as this can change the clinical outcome of these patients with cardiovascular abnormalities in liver cirrhosis.
This study aims to determine the prevalence of pulmonary hypertension in LC patients.
A cross-sectional analytical study was carried out at JUTH (Jos University Teaching Hospital) over a period of one year. We recruited 210 adult patients with liver cirrhosis from the gastroenterology clinic and wards for this study. Data from these patients were collected with questionnaires administered by the interviewer and analysed using SPSS 23 statistical software (IBM Corp., Armonk, NY). The data obtained are presented in tables and charts. Categorical variables were expressed as proportions and frequencies, while continuous data were expressed as the median, mean, and standard deviation.
Pulmonary hypertension was found in 30.5% of the participants, with mild pulmonary hypertension being the most common. No one had severe pulmonary hypertension. There was an increased risk of developing pulmonary hypertension in patients with coughs, easy fatigability, bilateral leg swelling, abdominal swelling, and ascites (P<0.05).
The result showed that there is a high prevalence of pulmonary hypertension in patients with liver cirrhosis.
肝硬化是慢性肝病的常见并发症。在过去几年中其患病率显著上升。肝硬化会引发心血管疾病的发病和死亡。通过超声心动图检测异常情况很重要，因为这可能会改变肝硬化合并心血管异常患者的临床结局。
本研究旨在确定肝硬化患者中肺动脉高压的患病率。
在乔斯大学教学医院（JUTH）进行了为期一年的横断面分析研究。我们从胃肠病科门诊和病房招募了210名成年肝硬化患者参与本研究。这些患者的数据通过访谈者发放的问卷收集，并使用SPSS 23统计软件（IBM公司，纽约州阿蒙克）进行分析。所获得的数据以表格和图表形式呈现。分类变量以比例和频率表示，而连续数据以中位数、均值和标准差表示。
30.5%的参与者被发现患有肺动脉高压，其中轻度肺动脉高压最为常见。无人患有重度肺动脉高压。咳嗽、易疲劳、双侧腿部肿胀、腹部肿胀和腹水患者发生肺动脉高压的风险增加（P<0.05）。
结果表明肝硬化患者中肺动脉高压的患病率很高。
