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一名新诊断为免疫性血小板减少性紫癜的患者因病毒感染引发脑出血。

Intracerebral Hemorrhage in a Patient With Newly Diagnosed Immune Thrombocytopenic Purpura Precipitated by a Viral Illness.

作者信息

Pongsakul Ann, Daniel Amy, Lochala Roddy, Martin David E

机构信息

Family Medicine, Unity Health, Searcy, USA.

Graduate Medical Education, Unity Health, Searcy, USA.

出版信息

Cureus. 2024 Mar 30;16(3):e57284. doi: 10.7759/cureus.57284. eCollection 2024 Mar.

DOI:10.7759/cureus.57284
PMID:38690508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11058587/
Abstract

Intracerebral hemorrhage (ICH) is a rare and severe complication of immune thrombocytopenic purpura (ITP) that can be spontaneous. Viral illnesses, other infections, autoimmune disorders, and medications can cause ITP. ITP causes a significant decrease in platelet levels, increasing bleeding risk. ITP can be treated by steroids, intravenous immunoglobulin, plasmapheresis, platelet transfusion, biological agents, and splenectomy. ICH treatment involves the treatment of underlying ITP, as well as any neuro-interventional procedures needed. In this case report, we look at the presenting symptoms and treatment course of an interesting case of ICH in a patient who developed ITP after a viral upper respiratory infection.

摘要

脑出血(ICH)是免疫性血小板减少性紫癜(ITP)一种罕见且严重的并发症,可为自发性。病毒感染性疾病、其他感染、自身免疫性疾病及药物均可导致ITP。ITP导致血小板水平显著下降,增加出血风险。ITP可通过使用类固醇、静脉注射免疫球蛋白、血浆置换、血小板输注、生物制剂及脾切除术进行治疗。ICH的治疗包括对潜在ITP的治疗以及所需的任何神经介入程序。在本病例报告中,我们探讨了一名在病毒性上呼吸道感染后发生ITP的患者发生ICH这一有趣病例的临床表现及治疗过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763a/11058587/ee52782b4746/cureus-0016-00000057284-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763a/11058587/e357de3960da/cureus-0016-00000057284-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763a/11058587/245a2ccd9840/cureus-0016-00000057284-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763a/11058587/ee52782b4746/cureus-0016-00000057284-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763a/11058587/e357de3960da/cureus-0016-00000057284-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763a/11058587/245a2ccd9840/cureus-0016-00000057284-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/763a/11058587/ee52782b4746/cureus-0016-00000057284-i03.jpg

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本文引用的文献

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Immune Thrombocytopenic Purpura in an Adult Male: A Case Report.一名成年男性的免疫性血小板减少性紫癜:病例报告
Cureus. 2023 Oct 8;15(10):e46664. doi: 10.7759/cureus.46664. eCollection 2023 Oct.
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Life-Threatening Intracerebral Hemorrhage in Adult with ITP: Challenging Entity.成人免疫性血小板减少症患者出现危及生命的脑出血:具有挑战性的情况。
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Cureus. 2022 Apr 24;14(4):e24447. doi: 10.7759/cureus.24447. eCollection 2022 Apr.
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COVID-19 induced immune thrombocytopenic purpura: case report.新型冠状病毒肺炎诱发的免疫性血小板减少性紫癜:病例报告
Stem Cell Investig. 2021 Jul 9;8:14. doi: 10.21037/sci-2020-060. eCollection 2021.
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Immune Thrombocytopenic Purpura in a Patient with Covid-19.一名新冠肺炎患者的免疫性血小板减少性紫癜
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Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis.血小板减少症与严重的 2019 年冠状病毒病(COVID-19)感染相关:一项荟萃分析。
Clin Chim Acta. 2020 Jul;506:145-148. doi: 10.1016/j.cca.2020.03.022. Epub 2020 Mar 13.
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Treatments for Primary Immune Thrombocytopenia: A Review.原发性免疫性血小板减少症的治疗:综述
Cureus. 2019 Oct 6;11(10):e5849. doi: 10.7759/cureus.5849.
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Immune Thrombocytopenia - Current Diagnostics and Therapy: Recommendations of a Joint Working Group of DGHO, ÖGHO, SGH, GPOH, and DGTI.免疫性血小板减少症——当前的诊断与治疗:德国血液学和肿瘤学学会、奥地利血液学和肿瘤学学会、瑞士血液学和肿瘤学学会、德国儿科学会和德国血栓与止血学会联合工作组的建议
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