Chang Nicholas, Lennard Kate, Rao Amshuman, Elliott Michael, Dharan Nila, Wong Johnny
Royal Prince Alfred Hospital, Department of Neurosurgery, Sydney, Australia.
Royal Prince Alfred Hospital, Department of Infectious Diseases, Sydney, Australia.
IDCases. 2024 Apr 15;36:e01960. doi: 10.1016/j.idcr.2024.e01960. eCollection 2024.
This article describes a case of polymicrobial pharyngitis and sinusitis complicated by intracranial complications and reviews similar cases in the literature.
A 21-year-old immunocompetent male presented with symptoms of sore throat, rhinorrhoea, lethargy, headache, and rash. Imaging demonstrated sinusitis, pre-septal sinusitis, peritonsillar abscess formation, subdural empyema and cerebritis. He was managed with endoscopic sinus surgery, craniotomy for evacuation of subdural empyema and antibiotics. Microbiological samples demonstrated growth of , , and . He subsequently developed a cerebral abscess requiring stereotactic needle drainage. After a prolonged course of antibiotics, the patient was discharge and made a good recovery.
is an uncommon cause of non-streptococcal pharyngitis that may occur alongside other microorganisms and is rarely associated with severe intracranial complications. This organism and its antibiotic susceptibility patterns should be considered in complicated upper respiratory tract infections in immunocompetent hosts. Penicillins and macrolide antibiotics form the mainstay of therapy for .
本文描述了一例多微生物性咽炎和鼻窦炎并发颅内并发症的病例,并回顾了文献中的类似病例。
一名21岁免疫功能正常的男性出现咽痛、流涕、嗜睡、头痛和皮疹症状。影像学检查显示鼻窦炎、鼻中隔前鼻窦炎、扁桃体周围脓肿形成、硬膜下积脓和脑炎。他接受了内镜鼻窦手术、开颅清除硬膜下积脓及抗生素治疗。微生物样本显示有[具体微生物1]、[具体微生物2]和[具体微生物3]生长。随后他发展为脑脓肿,需要立体定向穿刺引流。经过长时间的抗生素治疗,患者出院并恢复良好。
[具体微生物名称]是非链球菌性咽炎的罕见病因,可能与其他微生物同时出现,很少与严重的颅内并发症相关。在免疫功能正常宿主的复杂性上呼吸道感染中应考虑这种微生物及其抗生素敏感性模式。青霉素和大环内酯类抗生素是治疗[具体微生物名称]的主要药物。