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妊娠高血压疾病的管理:欧洲高血压学会工作组“女性高血压”的立场声明。

Management of hypertensive disorders in pregnancy: a Position Statement of the European Society of Hypertension Working Group 'Hypertension in Women'.

机构信息

Department of Cardiology, General Hospital of Athens 'Laiko', Athens, Greece.

Department of Hypertension, University Medical Centre Ljubljana, Medical University Ljubljana, Slovenia.

出版信息

J Hypertens. 2024 Jul 1;42(7):1109-1132. doi: 10.1097/HJH.0000000000003739. Epub 2024 Apr 11.

Abstract

Hypertensive disorders in pregnancy (HDP), remain the leading cause of adverse maternal, fetal, and neonatal outcomes. Epidemiological factors, comorbidities, assisted reproduction techniques, placental disorders, and genetic predisposition determine the burden of the disease. The pathophysiological substrate and the clinical presentation of HDP are multifarious. The latter and the lack of well designed clinical trials in the field explain the absence of consensus on disease management among relevant international societies. Thus, the usual clinical management of HDP is largely empirical. The current position statement of the Working Group 'Hypertension in Women' of the European Society of Hypertension (ESH) aims to employ the current evidence for the management of HDP, discuss the recommendations made in the 2023 ESH guidelines for the management of hypertension, and shed light on controversial issues in the field to stimulate future research.

摘要

妊娠高血压疾病(HDP)仍然是导致孕产妇、胎儿和新生儿不良结局的主要原因。流行病学因素、合并症、辅助生殖技术、胎盘疾病和遗传易感性决定了疾病的负担。HDP 的病理生理基础和临床表现是多种多样的。后者以及该领域缺乏精心设计的临床试验解释了相关国际协会之间在疾病管理方面缺乏共识。因此,HDP 的常规临床管理在很大程度上是经验性的。欧洲高血压学会(ESH)“女性高血压”工作组的当前立场声明旨在利用当前 HDP 管理的证据,讨论 2023 年 ESH 高血压管理指南中的建议,并阐明该领域有争议的问题,以激发未来的研究。

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