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Trial Update of Pitavastatin to Prevent Cardiovascular Events in HIV Infection.

作者信息

Grinspoon Steven K, Ribaudo Heather J, Douglas Pamela S

机构信息

Massachusetts General Hospital, Boston, MA

Harvard T.H. Chan School of Public Health, Boston, MA.

出版信息

N Engl J Med. 2024 May 2;390(17):1626-1628. doi: 10.1056/NEJMc2400870.

DOI:10.1056/NEJMc2400870
PMID:38692296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11403456/
Abstract
摘要

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Reply: Calcified vs Noncalcified Plaque in HIV Revisited: Insights From REPRIEVE.回复:重新审视HIV中的钙化斑块与非钙化斑块:来自REPRIEVE研究的见解
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No evidence of a detrimental effect of pitavastatin on neurocognitive function among people with HIV.没有证据表明匹伐他汀对艾滋病毒感染者的神经认知功能有不利影响。

本文引用的文献

1
Pitavastatin to Prevent Cardiovascular Disease in HIV Infection.匹伐他汀预防 HIV 感染患者的心血管疾病。
N Engl J Med. 2023 Aug 24;389(8):687-699. doi: 10.1056/NEJMoa2304146. Epub 2023 Jul 23.
AIDS. 2025 Jun 12. doi: 10.1097/QAD.0000000000004267.
4
Prognostic Factors of Physical Function Decline Among Middle-Aged Adults With HIV.感染HIV的中年成年人身体功能下降的预后因素
Open Forum Infect Dis. 2025 May 27;12(6):ofaf311. doi: 10.1093/ofid/ofaf311. eCollection 2025 Jun.
5
REPRIEVE final results: What does it mean for guidelines in low- and middle-income countries?暂缓执行试验的最终结果:这对低收入和中等收入国家的指南意味着什么?
J Int AIDS Soc. 2025 Jun;28(6):e26525. doi: 10.1002/jia2.26525.
6
Effects of antiretrovirals on major adverse cardiovascular events in the REPRIEVE trial: a longitudinal cohort analysis.抗逆转录病毒药物对“延缓艾滋病毒感染进程”(REPRIEVE)试验中主要不良心血管事件的影响:一项纵向队列分析
Lancet HIV. 2025 Jul;12(7):e496-e505. doi: 10.1016/S2352-3018(25)00043-8. Epub 2025 Jun 4.
7
Risks for sudden cardiac and undetermined cause of death among people with HIV in the reprieve primary cardiovascular prevention trial.在“缓刑”原发性心血管预防试验中,HIV感染者发生心源性猝死和不明原因死亡的风险。
AIDS. 2025 May 23. doi: 10.1097/QAD.0000000000004243.
8
Statin Therapy as Primary Prevention for Persons With HIV: A Synopsis of Recommendations From the U.S. Department of Health and Human Services Antiretroviral Treatment Guidelines Panel.他汀类药物治疗作为HIV感染者的一级预防:美国卫生与公众服务部抗逆转录病毒治疗指南小组建议概述
Ann Intern Med. 2025 Jun;178(6):847-857. doi: 10.7326/ANNALS-24-03564. Epub 2025 May 27.
9
Balancing polypharmacy and comorbidity management: cardiovascular health.平衡多重用药与共病管理:心血管健康
Curr Opin HIV AIDS. 2025 Jul 1;20(4):409-415. doi: 10.1097/COH.0000000000000948. Epub 2025 May 13.
10
Coronary Plaque, Inflammation, Subclinical Myocardial Injury, and Major Adverse Cardiovascular Events in the REPRIEVE Substudy.REPRIEVE子研究中的冠状动脉斑块、炎症、亚临床心肌损伤及主要不良心血管事件
JACC Adv. 2025 May 14;4(6 Pt 1):101781. doi: 10.1016/j.jacadv.2025.101781.