标准化戒烟方案对长期康复中成瘾患者心理生理参数的影响：一项准实验性试点研究。
The effectiveness of a standardized tobacco cessation program on psychophysiological parameters in patients with addiction undergoing long-term rehabilitation: a quasi-experimental pilot study.
机构信息
Department of Psychoanalysis and Psychotherapy, Medical University Vienna, Vienna, Austria.
Center for Integrative Addiction Research (CIAR), Grüner Kreis Society, Vienna, Austria.
出版信息
BMC Med. 2024 May 1;22(1):184. doi: 10.1186/s12916-024-03405-z.
BACKGROUND
Although there is a very high comorbidity between tobacco dependence and other addictive disorders, there are only few studies examining the implementation and outcomes of a tobacco cessation program in patients with addictive diseases. Therefore, the aim of this study is to investigate to what extent a standardized tobacco cessation program leads to improvements regarding psychological/physical parameters in patients with addiction undergoing therapy and whether there is a reduction in tobacco consumption.
METHODS
The study took place in a therapeutic community specialized in addiction therapy. A total sample of 56 participants were non-randomly assigned to an intervention group (IG; n = 31) and a treatment as usual group (TAUG; n = 25). The IG participated in a 6-week tobacco cessation program, while the TAUG received no additional treatment. Both groups were assessed for changes in primary outcomes (tobacco dependence, smoked cigarettes per day (CPD), and general substance-related craving) and secondary outcomes (heart rate variability (HRV): root mean square of successive differences, self-efficacy, and comorbid psychiatric symptoms) at two measurement time points (pre- and post-treatment/6 weeks).
RESULTS
We observed significant improvements in self-efficacy (F = 5.86; p < .05; η = .11) and decreased CPD in the IG (β = 1.16, ρ < .05), while no significant changes were observed in the TAUG. No significant interaction effects were observed in psychiatric symptoms, general substance-related craving, and HRV.
CONCLUSIONS
The results highlight the potential benefit of an additional tobacco cessation program as part of a general addiction treatment. Although no improvements in the physiological domain were observed, there were significant improvements regarding self-efficacy and CPD in the IG compared to the TAUG. Randomized controlled trials on larger samples would be an important next step.
TRIAL REGISTRATION
ISRCTN15684371.
背景
尽管烟草依赖与其他成瘾障碍之间存在很高的共病率，但仅有少数研究探讨了在成瘾疾病患者中实施和评估戒烟计划的效果。因此，本研究旨在调查标准化戒烟计划在接受治疗的成瘾患者中在心理/生理参数方面的改善程度，以及是否能减少烟草消耗。
方法
该研究在一家专门从事成瘾治疗的治疗社区进行。共有 56 名参与者被非随机分配到干预组（IG；n=31）和常规治疗组（TAUG；n=25）。IG 参加了为期 6 周的戒烟计划，而 TAUG 则未接受任何额外的治疗。两组均在两个测量时间点（治疗前/6 周）评估主要结局（烟草依赖、每天吸烟量（CPD）和一般物质相关渴求）和次要结局（心率变异性（HRV）：连续差异的均方根、自我效能感和共病精神症状）的变化。
结果
我们观察到自我效能感（F=5.86；p<.05；η=0.11）显著改善，IG 组的 CPD 减少（β=1.16，p<.05），而 TAUG 组则没有显著变化。在精神病症状、一般物质相关渴求、HRV 方面未观察到显著的交互效应。
结论
结果突出了作为一般成瘾治疗的一部分，额外的戒烟计划的潜在益处。尽管在生理领域没有观察到改善，但与 TAUG 相比，IG 在自我效能感和 CPD 方面有显著改善。在更大的样本量上进行随机对照试验将是下一步的重要步骤。
试验注册
ISRCTN84305522。
Zotero 插件