Mahmood Khalid, Ahmad Ahsan, Upadhyay Rohit, Khatoon Takallum, Imbisat Zaid, Akela Ankur
Department of Urology, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Department of Anaesthesiology, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Cureus. 2024 Mar 31;16(3):e57363. doi: 10.7759/cureus.57363. eCollection 2024 Mar.
End-stage renal disease (ESRD) rates are on the rise globally, including in India. However, the affordability of dialysis treatment remains a significant challenge for many, with costs varying across different regions. Although cost-effective, kidney transplantation faces challenges like a surgeon shortage, lack of infrastructure, and lack of logistic support. The study examines Indian laparoscopic nephrectomy outcomes and their benefits for donor recovery. It covers kidney donor procedural details, demographics, preoperative health evaluations, complications, and one-month follow-up.
Ethical approval was obtained, and the study involved 102 cases at the Indira Gandhi Institute of Medical Science, Patna, Bihar, India, from 2019 to 2023. Detailed preoperative assessments, postoperative complications, and one-month follow-up analyses were conducted. Statistical analysis employed SPSS version 17 (IBM Corp., Armonk, NY).
The results revealed an average surgery time of 152.3 min, blood loss of 205 ± 42 ml, and a hospital stay of 4.6 ± 2.2 days. The study found a female predominance (80.39%), with a mean donor age of 35.9 ± 5.2 years. Preoperative assessments showed robust patient health, with glomerular filtration rate (GFR) exceeding the expected threshold and normal urea levels, creatinine, electrolytes, liver enzymes, bilirubin, albumin, and total protein. Post-nephrectomy complications were reported, with females experiencing more difficulties than males.
This study underscores the efficiency and safety of laparoscopic nephrectomy in the Indian context, providing valuable insights into donor demographics, preoperative health assessments, complications, and postoperative outcomes. The findings contribute to understanding laparoscopic nephrectomy outcomes and associated risk factors despite certain limitations.
全球范围内，包括印度，终末期肾病（ESRD）的发病率都在上升。然而，透析治疗的可负担性对许多人来说仍是一项重大挑战，不同地区的费用各不相同。尽管肾移植具有成本效益，但面临着诸如外科医生短缺、基础设施不足和缺乏后勤支持等挑战。本研究考察了印度腹腔镜肾切除术的结果及其对供体恢复的益处。它涵盖了肾脏供体的手术细节、人口统计学特征、术前健康评估、并发症以及1个月的随访情况。
本研究获得了伦理批准，纳入了2019年至2023年期间在印度比哈尔邦巴特那市英迪拉·甘地医学科学研究所的102例病例。进行了详细的术前评估、术后并发症及1个月随访分析。统计分析采用SPSS 17版（IBM公司，纽约州阿蒙克）。
结果显示平均手术时间为152.3分钟，失血量为205±42毫升，住院时间为4.6±2.2天。研究发现女性占主导（80.39%），供体平均年龄为35.9±5.2岁。术前评估显示患者健康状况良好，肾小球滤过率（GFR）超过预期阈值，尿素水平、肌酐、电解质、肝酶、胆红素、白蛋白和总蛋白均正常。报告了肾切除术后的并发症，女性比男性经历了更多困难。
本研究强调了在印度背景下腹腔镜肾切除术的有效性和安全性，为供体人口统计学特征、术前健康评估、并发症及术后结果提供了有价值的见解。尽管存在某些局限性，但这些发现有助于了解腹腔镜肾切除术的结果及相关风险因素。
