Chahed Norashikin, Dzulkarnain Ahmad Aidil Arafat, Jamaluddin Saiful Adli
Department of Audiology and Speech-Language Pathology, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Pahang, Malaysia.
Audiology Unit, Otorhinolaryngology Department, Hospital Ampang, Ministry of Health of Malaysia, Malaysia.
Malays J Med Sci. 2024 Apr;31(2):62-71. doi: 10.21315/mjms2024.31.2.7. Epub 2024 Apr 23.
Auditory brainstem response (ABR) to the level-specific (LS) CE-Chirp has been reported to provide optimum neural synchrony along cochlear partitions, theoretically improving ABR waveform resolution. Despite this promising finding, limited studies have been conducted to contrast the results between LS CE-Chirp and Click stimuli. The current study aimed to compare the results of ABR between the two stimuli (Click and LS CE-Chirp).
Sixty-seven normal-hearing infants, both with and without risk factors, aged less than 7 months old, participated in this study. The ABR test was conducted at 70 dBnHL using 33.3 stimulus repetition rates with both Click and LS CE-Chirp stimuli. The signal averaging was stopped at a maximum fixed signal average of 2,500 sweeps. Data were statistically compared between the two stimuli using the Wilcoxon signed-rank test.
The waves I and V ABRs elicited by LS CE-Chirp exhibited significantly larger amplitudes than the Click stimulus. However, the amplitude of wave III and absolute latencies were similar in both stimuli at a supra-threshold level.
LS CE-Chirp has the advantage of larger amplitudes than the ABR from Click at the supra-threshold level (70 dBnHL) in normal-hearing infants.
据报道，听觉脑干反应（ABR）对特定水平（LS）的CE-Chirp刺激能在耳蜗分区上提供最佳的神经同步性，从理论上讲可提高ABR波形分辨率。尽管有这一有前景的发现，但对比LS CE-Chirp和短声刺激结果的研究却很有限。本研究旨在比较这两种刺激（短声和LS CE-Chirp）下的ABR结果。
67名年龄小于7个月、有或无风险因素的听力正常婴儿参与了本研究。ABR测试在70 dBnHL下进行，短声和LS CE-Chirp刺激的刺激重复率均为33.3次/秒。信号平均在最大固定信号平均次数为2500次扫描时停止。使用Wilcoxon符号秩检验对两种刺激的数据进行统计学比较。
LS CE-Chirp引出的ABR波I和波V的振幅明显大于短声刺激。然而，在阈上水平，两种刺激下的波III振幅和绝对潜伏期相似。
在听力正常的婴儿中，在阈上水平（70 dBnHL），LS CE-Chirp比短声引出的ABR具有更大振幅的优势。
