Cytauxzoonosis in Indiana, USA: a case series of cats infected with (2018-2022).

CASE SERIES SUMMARY

This case series describes six cases involving seven cats naturally infected with in Indiana, USA. Medical records were retrospectively reviewed and all available information on signalment, history, clinical and diagnostic findings, treatment, outcome and pathology was reported. Cats infected with were domestic shorthairs, were aged between 2 and 9 years and all but one of the cats were male. The seven infected cats originated from five counties in southwestern Indiana. Six of seven cats were found to have acute cytauxzoonosis based on clinical signs, gross pathologic lesions, observation of in tissues and/or detection of DNA. One cat was identified as a subclinical survivor cat with no known clinical history of cytauxzoonosis.

RELEVANCE AND NOVEL INFORMATION

The reported cases are the first confirmed reports of acute and chronic cytauxzoonosis in cats from Indiana and document an expansion in the range of . Veterinary practitioners in Indiana should consider infection with as a differential diagnosis for cats that present with fever, inappetence, lethargy, depression, dehydration, dyspnea, hemolytic crisis, anorexia or icterus. Administration of approved acaricides to cats currently offers the best protection and control against infection.