Wikander Yvonne M, Kang Qing, Reif Kathryn E
Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.
Department of Statistics, College of Arts and Sciences, Kansas State University, Manhattan, KS 66506, USA.
Vet Sci. 2020 Dec 18;7(4):205. doi: 10.3390/vetsci7040205.
, a tick-borne hemoprotozoal pathogen of felids, causes an acute, often-fatal disease in domestic cats. While public awareness of the disease has increased, few studies have evaluated the incidence of acute cytauxzoonosis cases and their associated risk factors. The objective of this study was to retrospectively review records of cats diagnosed with acute cytauxzoonosis in eastern Kansas from 2006-2019 using clinic records and determine: (i) feline cytauxzoonosis risk factors; and (ii) if cytauxzoonosis case incidence is increasing. Although inter-annual variation of acute cytauxzoonosis diagnosis was observed in the eastern Kansas domestic cat population, the overall incidence trend remained largely unchanged over the 14-year case review period. In comparison to ill (-unrelated) control cases, more acute cytauxzoonosis cases were diagnosed in spring and summer, suggesting a seasonal fluctuation of infection, with samples most commonly submitted from ≥1 year old, owned, male cats. Although cytauxzoonosis case submissions remained consistent over the broad study period, increasing tick vector and domestic cat reservoir populations may contribute to additional cytauxzoonosis case expansion in endemic areas. Investigating the incidence of acute cytauxzoonosis, patient risk factors, and ecological variables that influence disease transmission are important steps towards developing and communicating the need for effective cytauxzoonosis control strategies for high-risk cat populations.
猫巴贝斯虫是一种通过蜱传播的猫科动物血液原虫病原体，可导致家猫患上急性、通常致命的疾病。虽然公众对该疾病的认识有所提高，但很少有研究评估急性猫巴贝斯虫病病例的发病率及其相关危险因素。本研究的目的是回顾性分析2006年至2019年堪萨斯州东部被诊断为急性猫巴贝斯虫病的猫的临床记录，并确定：（i）猫巴贝斯虫病的危险因素；（ii）猫巴贝斯虫病病例发病率是否在上升。尽管在堪萨斯州东部家猫群体中观察到急性猫巴贝斯虫病诊断的年际变化，但在14年的病例回顾期内，总体发病率趋势基本保持不变。与患病（无关联）对照病例相比，春季和夏季诊断出的急性猫巴贝斯虫病病例更多，这表明感染存在季节性波动，样本最常来自≥1岁的家养雄性猫。尽管在广泛的研究期间猫巴贝斯虫病病例提交情况保持一致，但蜱传播媒介和家猫宿主数量的增加可能会导致流行地区猫巴贝斯虫病病例进一步增加。调查急性猫巴贝斯虫病的发病率、患者危险因素以及影响疾病传播的生态变量，是制定和宣传针对高危猫群体的有效猫巴贝斯虫病控制策略需求的重要步骤。
