Li Jiayi, Shao Zikun, Yang Zhenzhen, Liu Pei, Sun Ning, Song Hongcheng, Xie Xianghui, Zhang Weiping
Department of Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health (NCCH), No. 56, Nanlishi Road, Yuetan Street, Xicheng District, Beijing, 100045, China.
World J Urol. 2024 May 2;42(1):282. doi: 10.1007/s00345-024-04965-8.
Pediatric hydronephrosis poses distinct challenges, particularly in cases involving horseshoe kidneys (HSK). This retrospective study compares treatment outcomes between HSK and non-horseshoe kidneys (NHSK) in pediatric ureteropelvic junction obstruction (UPJO) patients.
A retrospective cohort study included 35 patients with HSK and 790 patients with NHSK undergoing pyeloplasty. Preoperative, intraoperative, and postoperative parameters were evaluated. Propensity score matching (PSM) balanced patient characteristics in the NHSK group.
In comparison with NHSK, HSK exhibited a higher crossing vessel incidence (51.6% vs. 5.12%, P < 0.001) and smaller preoperative anteroposterior pelvic diameter (APD). Post 6 and 12 months, NHSK maintained a larger APD, with a higher P/C ratio at 12 months. PSM retained significantly higher crossing vessel incidence in HSK (51.6 vs. 3.61%, P < 0.001). Laparoscopic pyeloplasty (LP) in HSK showed lower postoperative length of stay (LOS). Postoperative ultrasound parameters favored NHSK. In HSK and NHSK with crossing vessels, HSK demonstrated higher complications even post-PSM (38.5% vs. 0%, P = 0.039).
The study emphasizes the importance of recognizing crossing vessels in HSK-related hydronephrosis. Surgical success, although comparable between HSK and NHSK, requires tailored approaches. This investigation contributes valuable insights to pediatric urology, emphasizing personalized management for optimal outcomes.
小儿肾积水带来了独特的挑战,尤其是在涉及马蹄肾(HSK)的病例中。这项回顾性研究比较了小儿肾盂输尿管连接部梗阻(UPJO)患者中马蹄肾和非马蹄肾(NHSK)的治疗结果。
一项回顾性队列研究纳入了35例接受肾盂成形术的马蹄肾患者和790例非马蹄肾患者。对术前、术中和术后参数进行了评估。倾向评分匹配(PSM)平衡了非马蹄肾组的患者特征。
与非马蹄肾相比,马蹄肾的交叉血管发生率更高(51.6%对5.12%,P<0.001),术前肾盂前后径(APD)更小。术后6个月和12个月时,非马蹄肾的APD更大,12个月时的P/C比值更高。PSM显示马蹄肾的交叉血管发生率仍显著更高(51.6%对3.61%,P<0.001)。马蹄肾患者行腹腔镜肾盂成形术(LP)后的住院时间(LOS)较短。术后超声参数更有利于非马蹄肾。在有交叉血管的马蹄肾和非马蹄肾患者中,即使在PSM后,马蹄肾的并发症发生率仍更高(38.5%对0%,P=0.039)。
该研究强调了识别马蹄肾相关肾积水交叉血管的重要性。虽然马蹄肾和非马蹄肾的手术成功率相当,但需要采用针对性的方法。这项研究为小儿泌尿外科提供了有价值的见解,强调个性化管理以实现最佳治疗效果。