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优化长期肠外营养的静脉通路

Optimizing Intravenous Access for Long-Term Parenteral Nutrition.

作者信息

Hurt Ryan T, Mohamed Elfadil Osman, Edakkanambeth Varayil Jithinraj, Bonnes Sara L, Salonen Bradley R, Mundi Manpreet S

机构信息

Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.

Division of Endocrinology, Mayo Clinic, Rochester, MN, USA.

出版信息

Curr Nutr Rep. 2024 Jun;13(2):323-330. doi: 10.1007/s13668-024-00534-y. Epub 2024 May 2.

Abstract

PURPOSE OF REVIEW

Securing safe and effective intravenous (IV) access is of utmost importance for administering parenteral nutrition (PN). Sustaining this access can indeed pose challenges, especially when dealing with the risk of complications associated with long-term PN. This review emphasizes best practices to optimize intravenous access and reviews the current evidence-based recommendations and consensus guidelines.

RECENT FINDINGS

An individualized approach when selecting central venous catheters (CVC) is recommended, considering the estimated duration of need for IV access and the number of lumens needed. Established and novel approaches to minimize complications, including infection and thrombosis, are recognized. These include placement and positioning of the catheter tip under sonographic guidance and the use of antimicrobial lock therapies. Moreover, when possible, salvaging CVCs can reduce the risk of vascular access loss. CVC selection for patients requiring PN depends on several factors. Carefully reviewing an individual patient's clinical characteristics and discussing options is important. Given the increased infection risk, CVC lumens should be minimized. For long-term PN beyond 6 months, using CVCs with skin barriers and larger diameters should be considered.

摘要

综述目的

确保安全有效的静脉通路对于胃肠外营养(PN)的给药至关重要。维持这种通路确实可能带来挑战,尤其是在应对与长期PN相关的并发症风险时。本综述强调优化静脉通路的最佳实践,并回顾当前基于证据的建议和共识指南。

最新发现

建议在选择中心静脉导管(CVC)时采用个体化方法,考虑静脉通路的估计所需持续时间和所需管腔数量。已认可的减少包括感染和血栓形成在内的并发症的既定方法和新方法。这些方法包括在超声引导下放置导管尖端并确定其位置,以及使用抗菌封管疗法。此外,尽可能挽救CVC可降低血管通路丧失的风险。为需要PN的患者选择CVC取决于多个因素。仔细评估个体患者的临床特征并讨论各种选择很重要。鉴于感染风险增加,应尽量减少CVC的管腔数量。对于超过6个月的长期PN,应考虑使用带有皮肤屏障且直径较大的CVC。

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