Suppr超能文献

头颈部血管异常的多学科管理

Interdisciplinary Management of Vascular Anomalies in the Head and Neck.

作者信息

Mattheis Stefan, Wanke Isabel

机构信息

Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Universitätsmedizin Essen (Direktor: Prof. Dr. Stephan Lang).

Zentrum für Neuroradiologie, Klinik Hirslanden, Zürich, Schweiz.

出版信息

Laryngorhinootologie. 2024 May;103(S 01):S125-S147. doi: 10.1055/a-2225-9932. Epub 2024 May 2.

Abstract

Vascular anomalies in the head and neck area are usually rare diseases and pose a particular diagnostic and therapeutic challenge. They are divided into vascular tumours and vascular malformations. A distinction is made between benign tumours, such as infantile haemangioma, and rare malignant tumours, such as angiosarcoma. Vascular malformations are categorised as simple malformations, mixed malformations, large vessel anomalies and those associated with other anomalies. Treatment is interdisciplinary and various modalities are available. These include clinical observation, sclerotherapy, embolisation, ablative and coagulating procedures, surgical resection and systemic drug therapy. Treatment is challenging, as vascular anomalies in the head and neck region practically always affect function and aesthetics. A better understanding of the genetic and molecular biological basis of vascular anomalies has recently led to clinical research into targeted drug therapies. This article provides an up-to-date overview of the diagnosis, clinic and treatment of vascular anomalies in the head and neck region.

摘要

头颈部血管异常通常是罕见疾病,在诊断和治疗上面临特殊挑战。它们分为血管肿瘤和血管畸形。良性肿瘤如婴儿血管瘤与罕见的恶性肿瘤如血管肉瘤有所区分。血管畸形分为单纯畸形、混合畸形、大血管异常以及与其他异常相关的血管畸形。治疗需要多学科协作,有多种治疗方式可供选择。这些方式包括临床观察、硬化治疗、栓塞、消融和凝固手术、手术切除以及全身药物治疗。由于头颈部血管异常几乎总会影响功能和美观,因此治疗颇具挑战性。最近,对头颈部血管异常的遗传和分子生物学基础的深入了解引发了针对靶向药物治疗的临床研究。本文对头颈部血管异常的诊断、临床情况及治疗进行了最新概述。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验