Department of Orthopedics, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
Department of Orthopedics, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
World Neurosurg. 2024 Jul;187:e749-e758. doi: 10.1016/j.wneu.2024.04.162. Epub 2024 May 1.
To investigate whether risk of new vertebral compression fractures (NVCFs) was associated with vicinity to treated vertebrae in percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCFs).
All OVCF (T6-L5) patients treated with PVP between January 2016 and December 2020 were retrospectively reviewed. Vicinity to treated vertebrae was defined as the number of vertebrae between an untreated and its closest treated level. The closest treated level was chosen as reference vertebra. Clinical, radiologic, and surgical parameters were compared between groups of reference vertebrae for each vicinity NVCF.
In total, 1348 patients with 1592 fractured and 14,584 normal vertebrae were enrolled. NVCF was identified in 20.1% (271 of 1348) patients in 2.2% (319 of 14584) vertebrae in a mean follow-up time of 24.3 ± 11.9 months. Rate of NVCF in vicinity 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11 level were 4.6% (130 of 2808), 2.4% (62 of 2558), 1.8% (42 of 2365), 1.5% (31 of 2131), 1.3% (23 of 1739), 1.3% (17 of 1298), 0.8% (7 of 847), 0.9% (4 of 450), 0.8% (2 of 245), 0.9% (1 of 117), and 0% (0 of 26), respectively. Rate of NVCF in vicinity 1 level was significantly higher than that in vicinity 2, 3, 4, 5, 6, 7, 8, and 9 level, respectively. However, compared to reference vertebrae for vicinity 1 NVCF, any clinical, radiologic, or surgical parameters were not significantly different in those for vicinity 2, 3, and 4 NVCF, respectively.
The closer vicinity to treated vertebrae in PVP, the higher rate of NVCF at follow-up. However, any clinical, radiologic, or surgical parameters might not matter in this phenomenon of vicinity-related NVCF.
探讨经皮椎体成形术（PVP）治疗骨质疏松性椎体压缩性骨折（OVCF）时，新椎体压缩性骨折（NVCF）的风险是否与邻近治疗椎体有关。
回顾性分析 2016 年 1 月至 2020 年 12 月期间接受 PVP 治疗的所有 OVCF（T6-L5）患者。邻近治疗椎体的定义为未治疗椎体与其最近的治疗水平之间的椎体数。最近的治疗水平被选为参考椎体。比较各组参考椎体的邻近 NVCF 的临床、放射学和手术参数。
共纳入 1348 例患者，1592 个骨折椎体和 14584 个正常椎体。在平均随访 24.3±11.9 个月后，20.1%（1348 例中的 271 例）患者和 2.2%（14584 个椎体中的 319 个）发生了 NVCF。邻近 1、2、3、4、5、6、7、8、9、10 和 11 个水平的 NVCF 发生率分别为 4.6%（2808 个中的 130 个）、2.4%（2558 个中的 62 个）、1.8%（2365 个中的 42 个）、1.5%（2131 个中的 31 个）、1.3%（1739 个中的 23 个）、1.3%（1298 个中的 17 个）、0.8%（847 个中的 7 个）、0.9%（450 个中的 4 个）、0.8%（245 个中的 2 个）、0.9%（117 个中的 1 个）和 0%（26 个中的 0 个）。邻近 1 水平的 NVCF 发生率明显高于邻近 2、3、4、5、6、7、8 和 9 水平。然而，与邻近 1 水平 NVCF 的参考椎体相比，邻近 2、3 和 4 水平 NVCF 的任何临床、放射学或手术参数均无显著差异。
PVP 中与治疗椎体越接近，随访时发生 NVCF 的几率越高。然而，在这种邻近相关的 NVCF 现象中，任何临床、放射学或手术参数可能都不重要。
