Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
J Equine Vet Sci. 2024 Jun;137:105075. doi: 10.1016/j.jevs.2024.105075. Epub 2024 May 1.
Placentitis is an important cause of reproductive losses in the equine industry. Many cases of clinical placentitis are not diagnosed until late in the course of the disease, and for this reason there is variability in the timing of intervention, diagnostic measurements, and treatment protocols. An 8-year-old multiparous Dutch Warmblood mare that was recently exposed to EHV-1 in the herd of origin presented for routine foaling management. Placentitis was diagnosed upon intake, and medical treatment was initiated. The mare delivered a term foal, and diagnostics for infectious etiology were unrewarding. While there were obvious clinical signs supporting a diagnosis of placentitis, histopathologic examination did not reveal active inflammatory lesions in the chorioallantois; however, severe funisitis was present. This report reviews early diagnosis and management of placentitis, demonstrates an array of classic and subtle pathologic lesions seen on microscopic examination, and discusses pathophysiology of placentitis.
胎膜炎是马业繁殖损失的一个重要原因。许多临床胎膜炎病例直到疾病晚期才被诊断出来，因此干预时机、诊断测量和治疗方案存在差异。一匹 8 岁的经产荷兰温血母马最近在原籍畜群中接触到 EHV-1，前来进行常规产驹管理。胎膜炎在入院时被诊断，并开始进行药物治疗。母马产下足月驹，传染病病因学诊断无结果。虽然有明显的临床症状支持胎膜炎的诊断，但组织病理学检查未显示绒毛膜尿囊膜炎有活动性炎症病变；然而，严重的脐带炎存在。本报告回顾了胎膜炎的早期诊断和治疗，展示了显微镜检查中可见的一系列典型和微妙的病理病变，并讨论了胎膜炎的病理生理学。
