Verri A P, Scattolin O, Nespoli L, Burgio G R
Pediatr Med Chir. 1985 Jul-Aug;7(4):545-8.
Thirty children in remission, at least one year after completing chemotherapy for Acute Lymphoblastic Leukemia, were assessed using general psychological measures. The Wechsler Intelligence tests were administered to evaluate their intellectual function: no significant reduction was found in overall IQ score. Only four of the patients, who presented neurological complications during the treatment, performed at lower levels. The group as a whole functioned poorly on tasks involving speeded performances and long-term memory. The age at diagnosis, the duration of the illness, the cranial irradiation and/or intrathecal-chemotherapy did not show any negative effects on the intellectual performance. Psycho-social adaptation was satisfactory: our patients do not show neurotic or psychotic disorders, but only affective disturbances (insecurity, irritability, poor self-perception, instability and depression). Familial adaptation was disturbed in 60% of the children and difficulty in socializing with peers was present in 57% of cases: the latter, in our experience, is related to poor self perception, present in 75% of our patients. We have found a more inadequate psycho-social adaptation in children who have not received any communication of their illness. Psychologic support can be of value for the child and his family in adapting to their difficult situation and in promoting a normal personality development of the child.
对30名急性淋巴细胞白血病化疗结束后至少缓解一年的儿童进行了一般心理测量评估。采用韦氏智力测验评估其智力功能：总体智商得分未发现显著降低。只有4名在治疗期间出现神经并发症的患者表现较差。该组整体在涉及快速表现和长期记忆的任务中表现不佳。诊断时的年龄、病程、头颅照射和/或鞘内化疗对智力表现均未显示出任何负面影响。心理社会适应情况令人满意：我们的患者未表现出神经症或精神病性障碍，仅存在情感障碍（不安全感、易怒、自我认知差、情绪不稳定和抑郁）。60%的儿童家庭适应受到干扰，57%的病例存在与同龄人社交困难的问题：根据我们的经验，后者与75%的患者存在的自我认知差有关。我们发现，未被告知病情的儿童心理社会适应更差。心理支持对于儿童及其家庭适应困难处境以及促进儿童正常人格发展可能具有价值。
