Infectious Disease Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
School of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
New Microbiol. 2024 May;47(1):15-27.
More than 800 million individuals have contracted SARSCOV2 infection worldwide. It was estimated that almost 10-20% of these might suffer from Long COVID. It is a multisystemic syndrome, which negatively affects the quality of life with a significant burden of health loss compared to COVID negative individuals. Moreover, the risk of sequelae still remains high at 2 years in both nonhospitalized and hospitalized individuals. This review summarizes studies regarding long COVID and clarifies the definitions, the risk factors and the management of this syndrome. Finally, it delves into the most frequent long-term outcomes, especially postural orthostatic tachycardia syndrome" (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), brain fog, and their therapeutical possibilities.
全球已有超过 8 亿人感染了 SARS-CoV-2。据估计，其中近 10-20%的人可能患有长新冠。这是一种多系统综合征，与新冠阴性个体相比，它对生活质量产生负面影响，导致严重的健康损失。此外，无论是非住院患者还是住院患者，2 年内仍存在较高的后遗症风险。本综述总结了关于长新冠的研究，阐明了该综合征的定义、危险因素和管理方法。最后，深入探讨了最常见的长期后果，特别是体位性心动过速综合征（POTS）、肌痛性脑脊髓炎/慢性疲劳综合征（ME/CFS）、脑雾及其治疗可能性。
